FAQ

Excitatory Amino Acid Antagonists

Known as: Antagonists, Glutamate Receptor, glutamate receptor antagonist, Antagonists, Excitatory Amino Acid 
Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2018
05019762018

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Narrower (44)

1-aminoindan-1,5-dicarboxylic acid1-hydroxy-3-amino-2-pyrrolidone2-Amino-5-phosphonovalerate2-Aminoadipic Acid
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In Bloodadministration & dosageaspects of radiation effectschemical synthesis
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Excitatory Amino Acid Antagonists
Phenobarbital
Ketamine
Dextromethorphan
Phencyclidine
Dizocilpine Maleate

Papers overview

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Highly Cited
2008
Highly Cited
2008
Autism-like behavioral phenotypes in BTBR T+tf/J mice.
Autism is a behaviorally defined neurodevelopmental disorder of unknown etiology. Mouse models with face validity to the core… (More)
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Highly Cited
2004
Highly Cited
2004
Neuroprotection in Ischemia Blocking Calcium-Permeable Acid-Sensing Ion Channels
Ca2+ toxicity remains the central focus of ischemic brain injury. The mechanism by which toxic Ca2+ loading of cells occurs in… (More)
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Highly Cited
2001
Highly Cited
2001
Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons.
Several studies have shown that the mesolimbic dopamine (DA) system is strongly influenced by the ventral subiculum (vSub) of the… (More)
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Highly Cited
2001
Highly Cited
2001
Increased cortical kynurenate content in schizophrenia.
BACKGROUND Metabolites of the kynurenine pathway of tryptophan degradation may play a role in the pathogenesis of several human… (More)
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Highly Cited
2001
Highly Cited
2001
Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia.
Kynurenic acid is an endogenous glutamate antagonist with a preferential action at the glycine-site of the N-methyl D-aspartate… (More)
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Highly Cited
1999
Highly Cited
1999
Multiple forms of LTP in hippocampal CA3 neurons use a common postsynaptic mechanism
We investigated long-term potentiation (LTP) at mossy fiber synapses on CA3 pyramidal neurons in the hippocampus. Using Ca2… (More)
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Highly Cited
1997
Highly Cited
1997
GABA in the nucleus accumbens shell participates in the central regulation of feeding behavior.
We have demonstrated previously that injections of 6, 7-dinitroquinoxaline-2,3-dione into the nucleus accumbens shell (AcbSh… (More)
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Highly Cited
1996
Highly Cited
1996
Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals.
A long-standing question in neurobiology is whether astrocytes respond to the neuronal release of neurotransmitters in vivo. To… (More)
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Highly Cited
1995
Highly Cited
1995
Refinement of odor molecule tuning by dendrodendritic synaptic inhibition in the olfactory bulb.
Mitral/tufted cells (M/T cells) and granule cells form reciprocal dendrodendritic synapses in the main olfactory bulb; the… (More)
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Highly Cited
1990
Highly Cited
1990
Glutamate, the dominant excitatory transmitter in neuroendocrine regulation.
Glutamate has been found to play an unexpectedly important role in neuroendocrine regulation in the hypothalamus, as revealed in… (More)
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