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Excitatory Amino Acid Antagonists

Known as: Antagonists, Glutamate Receptor, glutamate receptor antagonist, Antagonists, Excitatory Amino Acid 
Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists.
National Institutes of Health

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1-aminoindan-1,5-dicarboxylic acid1-hydroxy-3-amino-2-pyrrolidone2-Amino-5-phosphonovalerate2-Aminoadipic Acid
In Bloodaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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Review
2007
Review
2007
The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention
Review
2002
Review
2002
Antioxidant Therapy in Acute Central Nervous System Injury: Current State
Free radicals are highly reactive molecules generated predominantly during cellular respiration and normal metabolism. Imbalance… 
Highly Cited
2001
Highly Cited
2001
Glutamatergic Afferents from the Hippocampus to the Nucleus Accumbens Regulate Activity of Ventral Tegmental Area Dopamine Neurons
Several studies have shown that the mesolimbic dopamine (DA) system is strongly influenced by the ventral subiculum (vSub) of the… 
Highly Cited
1999
Highly Cited
1999
Single Synaptic Events Evoke NMDA Receptor–Mediated Release of Calcium from Internal Stores in Hippocampal Dendritic Spines
Review
1998
Review
1998
Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia.
Certain animal models can greatly enhance our understanding of the neurobiology of schizophrenia and can be used to predict the… 
Highly Cited
1996
Highly Cited
1996
Excitatory GABA Responses in Embryonic and Neonatal Cortical Slices Demonstrated by Gramicidin Perforated-Patch Recordings and Calcium Imaging
Gramicidin perforated-patch-clamp recordings in brain slices were used to obtain an accurate assessment of the developmental… 
Highly Cited
1993
Highly Cited
1993
Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention
Periventricular white matter injury, the principal variety of brain injury of the human premature infant, involves… 
Highly Cited
1990
Highly Cited
1990
Glutamate, the dominant excitatory transmitter in neuroendocrine regulation.
Glutamate has been found to play an unexpectedly important role in neuroendocrine regulation in the hypothalamus, as revealed in… 
Highly Cited
1988
Highly Cited
1988
The glutamate antagonist MK‐801 reduces focal ischemic brain damage in the rat
Excessive activation of the N‐methyl‐D‐aspartate (NMDA) subtype of glutamate receptor has been implicated in the sequence of… 
Highly Cited
1982
Highly Cited
1982
Anticonvulsant action of excitatory amino acid antagonists.
Compounds that antagonize neuronal excitation induced by dicarboxylic amino acids were tested in two animal models of epilepsy… 
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