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Excitatory Amino Acid Antagonists

Known as: Antagonists, Glutamate Receptor, glutamate receptor antagonist, Antagonists, Excitatory Amino Acid 
Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Autism is a behaviorally defined neurodevelopmental disorder of unknown etiology. Mouse models with face validity to the core… Expand
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Highly Cited
2004
Highly Cited
2004
Ca2+ toxicity remains the central focus of ischemic brain injury. The mechanism by which toxic Ca2+ loading of cells occurs in… Expand
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Review
1998
Review
1998
Certain animal models can greatly enhance our understanding of the neurobiology of schizophrenia and can be used to predict the… Expand
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Highly Cited
1997
Highly Cited
1997
Subanesthetic doses of ketamine, a noncompetitive NMDA receptor antagonist, impair prefrontal cortex (PFC) function in the rat… Expand
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Highly Cited
1996
Highly Cited
1996
Gramicidin perforated-patch-clamp recordings in brain slices were used to obtain an accurate assessment of the developmental… Expand
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Review
1995
Review
1995
BACKGROUND Excitotoxic damage due to excess release of neuronal glutamate is hypothesized to play a pivotal role in the… Expand
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Highly Cited
1994
Highly Cited
1994
NEUROTRANSMITTER released from neurons is known to signal to neighbouring neurons and glia1–3 Here we demonstrate an additional… Expand
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Highly Cited
1990
Highly Cited
1990
Glutamate has been found to play an unexpectedly important role in neuroendocrine regulation in the hypothalamus, as revealed in… Expand
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Highly Cited
1989
Highly Cited
1989
Intrathecal administration of glycine (strychnine) or GABA (bicuculline) but not opioid (naloxone), adrenergic (phentolamine) or… Expand
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Highly Cited
1982
Highly Cited
1982
Compounds that antagonize neuronal excitation induced by dicarboxylic amino acids were tested in two animal models of epilepsy… Expand
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