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2-Amino-5-phosphonovalerate

Known as: 2-Amino-5-phosphonopentanoate, 2 Amino 5 phosphonovalerate, 2-Amino-5-phosphonovalerate [Chemical/Ingredient] 
The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA… 
National Institutes of Health

Related topics

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15 relations

Narrower (5)

2-amino-5-phosphono-3-pentenoic acid2-amino-7-phosphonoheptanoic acidCGP 39551CGP 39653

Broader (1)

Excitatory Amino Acid Antagonists
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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Highly Cited
1996
Highly Cited
1996
Decrement of GABAA receptor-mediated inhibitory postsynaptic currents in dentate granule cells in epileptic hippocampus.
1. Inhibitory postsynaptic currents (IPSCs) were studied in hippocampal dentate granule cells (DGCs) in the pilocarpine model and… 
Highly Cited
1992
Highly Cited
1992
Brainstem excitatory amino acid receptors in nociception: Microinjection mapping and pharmacological characterization of glutamate-sensitive sites in the brainstem associated with algogenic behavior
Highly Cited
1990
Highly Cited
1990
GABAB receptors play a major role in paired-pulse facilitation in area CA1 of the rat hippocampus
Highly Cited
1989
Highly Cited
1989
Blockade of NMDA-receptors prevents ocularity changes in kitten visual cortex after reversed monocular deprivation.
Highly Cited
1989
Highly Cited
1989
Formation of long-term potentiation in superior colliculus slices from the guinea pig
Highly Cited
1989
Highly Cited
1989
The development of N-methyl-D-aspartate receptors in cat visual cortex.
Highly Cited
1989
Highly Cited
1989
Excitatory amino acid-mediated components of synaptically evoked input from dorsal roots to deep dorsal horn neurons in the rat spinal cord slice
Highly Cited
1986
Highly Cited
1986
Synaptic excitation in cultures of mouse spinal cord neurones: receptor pharmacology and behaviour of synaptic currents.
Fast monosynaptic excitatory post‐synaptic potentials between spinal cord neurones in cell culture (s.c.‐s.c. e.p.s.p.s) were… 
Highly Cited
1984
Highly Cited
1984
A possible correlate of the postsynaptic condition for long-lasting potentiation in the guinea pig hippocampus in vitro
Highly Cited
1981
Highly Cited
1981
Pharmacological antagonists of excitant amino acid action.
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