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1-hydroxy-3-amino-2-pyrrolidone

Known as: 1-hydroxy-3-aminopyrrolidin-2-one, DL-1-hydroxy-3-amino-2-pyrrolidinone, 3-amino-1-hydroxypyrrolidone 
 
National Institutes of Health

Papers overview

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2008
2008
N-Methyl-D-aspartate (NMDA) receptors play a critical role in both development of the central nervous system and adult… Expand
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Highly Cited
2001
Highly Cited
2001
N-Methyl-d-aspartate (NMDA) receptors (NRs) are ionotropic receptors activated by glutamate and the co-agonist glycine. Ethanol… Expand
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2001
2001
Results from lesion studies show that selective damage to the temporal cortex or lateral entorhinal cortex impairs visual memory… Expand
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1997
1997
The neuroprotective effects of (R)-HA-966 and (S)-HA-966 (3-amino-1-hydroxy-2-pyrrolidinone) were examined in an MPTP (1-methyl-4… Expand
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1997
1997
N-Methyl-D-aspartate (NMDA)/glycine site antagonists were tested for their ability to prevent cocaine-induced convulsions and… Expand
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1995
1995
Male Sprague-Dawley rats underwent experimentally induced cardiac arrest and resuscitation, subsequently exhibiting involuntary… Expand
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1993
1993
Competitive and non-competitive NMDA receptor complex antagonists have been shown to be active in various models of anxiolytic… Expand
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1991
1991
HA-966 is an antagonist at the glycine modulatory site of N-methyl-D-aspartate (NMDA) receptors. Neuroprotective effects of HA… Expand
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1990
1990
Activation of the N-methyl-D-aspartate (NMDA) receptor complex is subject to modulation via interactions at a coupled [3H]glycine… Expand
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1982
1982
1. In experiments examining the possibility that an excitatory amino acid may be an optic nerve transmitter in mammals… Expand
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