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1-hydroxy-3-amino-2-pyrrolidone

Known as: 1-hydroxy-3-aminopyrrolidin-2-one, DL-1-hydroxy-3-amino-2-pyrrolidinone, 3-amino-1-hydroxypyrrolidone 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Excitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsPyrrolidinones

Narrower (1)

HA-966

Papers overview

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Highly Cited
2001
Highly Cited
2001
Ethanol Inhibition ofN-Methyl-d-aspartate Receptors Is Reduced by Site-directed Mutagenesis of a Transmembrane Domain Phenylalanine Residue*
N-Methyl-d-aspartate (NMDA) receptors (NRs) are ionotropic receptors activated by glutamate and the co-agonist glycine. Ethanol… 
2001
2001
Interference with visual memory in rats following infusion of the functional NMDA receptor antagonist, HA-966, into temporal regions.
1997
1997
Neuroprotective effects of the strychnine-insensitive glycine site NMDA antagonist (R)-HA-966 in an experimental model of Parkinson's disease
1997
1997
Novel NMDA/glycine site antagonists attenuate cocaine-induced behavioral toxicity.
1995
1995
Strychnine-insensitive glycine site antagonists attenuate a cardiac arrest-induced movement disorder.
Highly Cited
1993
Highly Cited
1993
Anxiolytic-like effects of N-methyl-D-aspartate-associated glycine receptor ligands in the rat potentiated startle test.
1991
1991
Different stereoselectivity of the enantiomers of HA-966 (3-amino-1-hydroxy-2-pyrrolidinone) for neuroprotective and anticonvulsant actions in vivo
1990
1990
Evidence for a functional coupling of the NMDA and glycine recognition sites in synaptic plasma membranes.
1990
1990
N‐Methyl‐D‐Aspartate Recognition Site Ligands Modulate Activity at the Coupled Glycine Recognition Site
Abstract: In synaptic plasma membranes from rat forebrain, the potencies of glycine recognition site agonists and antagonists for… 
Highly Cited
1982
Highly Cited
1982
The nature of the excitatory transmitter mediating X and Y cell inputs to the cat dorsal lateral geniculate nucleus
1. In experiments examining the possibility that an excitatory amino acid may be an optic nerve transmitter in mammals… 
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