1-hydroxy-3-amino-2-pyrrolidone

N-Methyl-D-aspartate (NMDA) receptors (NRs) are ionotropic receptors activated by glutamate and the co-agonist glycine. Ethanol… (More)

Results from lesion studies show that selective damage to the temporal cortex or lateral entorhinal cortex impairs visual memory… (More)

The neuroprotective effects of (R)-HA-966 and (S)-HA-966 (3-amino-1-hydroxy-2-pyrrolidinone) were examined in an MPTP (1-methyl-4… (More)

N-Methyl-D-aspartate (NMDA)/glycine site antagonists were tested for their ability to prevent cocaine-induced convulsions and… (More)

Male Sprague-Dawley rats underwent experimentally induced cardiac arrest and resuscitation, subsequently exhibiting involuntary… (More)

Competitive and non-competitive NMDA receptor complex antagonists have been shown to be active in various models of anxiolytic… (More)

HA-966 is an antagonist at the glycine modulatory site of N-methyl-D-aspartate (NMDA) receptors. Neuroprotective effects of HA… (More)

Activation of the N-methyl-D-aspartate (NMDA) receptor complex is subject to modulation via interactions at a coupled [3H]glycine… (More)

In synaptic plasma membranes from rat forebrain, the potencies of glycine recognition site agonists and antagonists for… (More)

1. In experiments examining the possibility that an excitatory amino acid may be an optic nerve transmitter in mammals… (More)