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HA-966

Known as: HA 966 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

1-hydroxy-3-amino-2-pyrrolidone

Papers overview

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Highly Cited
2002
Highly Cited
2002
Facilitation of Conditioned Fear Extinction by Systemic Administration or Intra-Amygdala Infusions of d-Cycloserine as Assessed with Fear-Potentiated Startle in Rats
NMDA receptor antagonists block conditioned fear extinction when injected systemically and also when infused directly into the… 
Highly Cited
1999
Highly Cited
1999
Characterization of MK-801-induced behavior as a putative rat model of psychosis.
The objective of this study was to characterize the behavior induced by the N-methyl-D-aspartate receptor antagonist MK-801… 
Highly Cited
1993
Highly Cited
1993
Desensitization of the NMDA receptor complex by glycinergic ligands in cerebellar granule cell cultures
Highly Cited
1992
Highly Cited
1992
Antinociceptive actions of different classes of excitatory amino acid receptor antagonists in mice.
Highly Cited
1991
Highly Cited
1991
Modulation of N-methyl-d-aspartate receptor-mediated increases in cytosolic calcium in cultured rat cerebellar granule cells
Highly Cited
1990
Highly Cited
1990
Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central nervous system effects: (+)-HA-966 is a selective glycine/N-methyl-D-aspartate receptor antagonist, but (-)-HA-966 is…
The antagonist effect of (+/-)-3-amino-1-hydroxypyrrolid-2-one (HA-966) at the N-methyl-D-aspartate (NMDA) receptor occurs… 
Highly Cited
1990
Highly Cited
1990
d-Cycloserine acts as a partial agonist at the glycine modulatory site of the NMDA receptor expressed inXenopus oocytes
Review
1989
Review
1989
The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system.
'The following abbreviations have been used in the text; I3-L-ODAP, I3-N-uxalyl-L-a,l3diaminu-prupiunic acid; ACPD, Trans-l-aminu… 
Highly Cited
1989
Highly Cited
1989
HA-966 antagonizes N-methyl-D-aspartate receptors through a selective interaction with the glycine modulatory site
3-Amino-1-hydroxypyrrolid-2-one (HA-966) has been known for several years as an excitatory amino acid antagonist, acting… 
Highly Cited
1982
Highly Cited
1982
The nature of the excitatory transmitter mediating X and Y cell inputs to the cat dorsal lateral geniculate nucleus
1. In experiments examining the possibility that an excitatory amino acid may be an optic nerve transmitter in mammals… 
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