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Calcium Channel Blockers

Known as: Blockers, Calcium Channel, Channel Blockers, Calcium, CCB 
A pharmaceutical agent that inhibits the movement of calcium across through calcium channels in the cell membrane, preventing or decreasing the… 
National Institutes of Health

Related topics

Related topics

48 relations

Narrower (41)

10 ML Nicardipine hydrochloride 2.5 MG/ML Injection12 HR Nicardipine hydrochloride 45 MG Extended Release Oral Capsule24 HR Diltiazem Hydrochloride 240 MG Extended Release Oral Capsule [Cardizem]24 HR Diltiazem Hydrochloride 240 MG Extended Release Oral Capsule [Tiazac]
Anti-Arrhythmia AgentsCalcium Channel Antagonists [MoA]Diltiazem HydrochlorideIn Blood

Broader (1)

ion channel blocker

Papers overview

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Review
2008
Review
2008
Calcium Antagonists for Aneurysmal Subarachnoid Hemorrhage
Graeme J. Hankey MD, FRCP Section Editor: Secondary ischemia is a frequent cause of poor outcome in patients with subarachnoid… 
Highly Cited
2005
Highly Cited
2005
Angiotensin-Converting Enzyme Inhibitors and Calcium Channel Blockers for Coronary Heart Disease and Stroke Prevention
We investigated whether protection from coronary heart disease (CHD) and stroke conferred by angiotensin-converting enzyme… 
Review
1994
Review
1994
Molecular basis for Ca2+ channel diversity.
Neurotransmitter release, neurosecretion, neuronal excitation, survival of neurons, and many other neuronal functions are… 
Highly Cited
1992
Highly Cited
1992
Dihydropyrimidine calcium channel blockers. 4. Basic 3-substituted-4-aryl-1,4-dihydropyrimidine-5-carboxylic acid esters. Potent antihypertensive agents.
We have examined a series of novel dihydropyrimidine calcium channel blockers that contain a basic group attached to either C5 or… 
Highly Cited
1989
Highly Cited
1989
Photochemical stroke model: flunarizine prevents sensorimotor deficits after neocortical infarcts in rats.
We produced unilateral photochemical infarcts in the hindlimb sensorimotor neocortex of 186 rats by intravenous injection of the… 
Highly Cited
1986
Highly Cited
1986
Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.
The metabolism of the dihydropyridine calcium antagonist and vasodilator nifedipine has been reported to exhibit polymorphism… 
Highly Cited
1984
Highly Cited
1984
Voltage‐Dependent Block of Calcium Channel Current in the Calf Cardiac Purkinje Fiber by Dihydropyridine Calcium Channel Antagonists
We have investigated the mechanisms of blockade of calcium channel current by the dihydropyridines, e.g. nisoldipine… 
Highly Cited
1984
Highly Cited
1984
Purification of the calcium antagonist receptor of the voltage-sensitive calcium channel from skeletal muscle transverse tubules.
[3H]Nitrendipine binds with high affinity to a calcium antagonist receptor preferentially localized to the transverse tubule… 
Highly Cited
1983
Highly Cited
1983
Novel dihydropyridines with positive inotropic action through activation of Ca2+ channels
Transmembrane influx of extracellular calcium through specific calcium channels is now accepted to have an important role in the… 
Review
1980
Review
1980
Calcium channel blocking agents in the treatment of cardiovascular disorders. Part II: Hemodynamic effects and clinical applications.
The calcium channel blocking agents have multiple hemodynamic effects that make them potentially valuable in treating many… 
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