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Calcium Channel Blockers

Known as: Blockers, Calcium Channel, Channel Blockers, Calcium, CCB 
A pharmaceutical agent that inhibits the movement of calcium across through calcium channels in the cell membrane, preventing or decreasing the… 
National Institutes of Health

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Narrower (41)

10 ML Nicardipine hydrochloride 2.5 MG/ML Injection12 HR Nicardipine hydrochloride 45 MG Extended Release Oral Capsule24 HR Diltiazem Hydrochloride 240 MG Extended Release Oral Capsule [Cardizem]24 HR Diltiazem Hydrochloride 240 MG Extended Release Oral Capsule [Tiazac]
Anti-Arrhythmia AgentsCalcium Channel Antagonists [MoA]Diltiazem HydrochlorideIn Blood

Broader (1)

ion channel blocker

Papers overview

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Highly Cited
1986
Highly Cited
1986
Suppression of Atherosclerosis in Cholesterol‐Fed Rabbits by Diltiazem Injection
The effects of diltiazem, a calcium antagonist, on the development of atherosclerosis were studied in Japanese white rabbits. The… 
Highly Cited
1986
Highly Cited
1986
Stereoselectivity of a potent calcium antagonist, 1-benzyl-3-pyrrolidinyl methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.
Four enantiomers (3a-d) of the title compound, YM-09730 (3), were synthesized by the reaction of (-)- or (+)-5-(methoxycarbonyl… 
Highly Cited
1985
Highly Cited
1985
Effect of Membrane Depolarization on Binding of [3H]Nitrendipine to Rat Cardiac Myocytes
Binding of the dihydropyridine calcium antagonist [3H]nitrendipine was studied in cardiac myocytes incubated in normal and high… 
Highly Cited
1984
Highly Cited
1984
No Effect of Nifedipine on Atherogenesis in Cholesterol‐Fed Rabbits
It was recently reported that the calcium antagonist nifedipine suppresses aortic cholesterol accumulation in cholesterol-fed… 
Highly Cited
1983
Highly Cited
1983
Identification of voltage operated calcium channels by binding studies: differentiation of subclasses of calcium antagonist drugs with 3H-nimodipine radioligand binding.
3H-Nimodipine (3H-NIM) is a high affinity radioligand suitable to study Ca2+ -channels in a variety of tissues. The binding is… 
Highly Cited
1982
Highly Cited
1982
Effects of PY 108–068, a New Calcium Antagonist, on General Hemodynamics and Regional Blood Flow in Anesthetized Cats: A Comparison with Nifedipine
The hemodynamic effects of PY 108–068 (PY), a new benzoxadiazolyle dihydropyridine derivative with calcium antagonistic effects… 
Highly Cited
1982
Highly Cited
1982
Binding of a calcium antagonist, [3H]nitrendipine, to high affinity sites in bovine aortic smooth muscle and canine cardiac membranes.
[(3)H]Nitrendipine, a potent calcium channel antagonist [3-ethyl-5-methyl-1-1,4-dihydro-2,6 - dimethyl - 4 - (3 - nitrophenyl… 
Highly Cited
1980
Highly Cited
1980
Autoradiographic method for measuring the ischemic myocardium at risk: effects of verapamil on infarct size aftr experimental coronary artery occlusion.
Investigation of the efficacy of pharmacologic agents affecting myocardial infarct size after coronary artery occlusion is… 
Highly Cited
1980
Highly Cited
1980
Changes in cardiac mechanics and coronary blood flow of regionally ischemic porcine myocardium induced by diltiazem.
The effect of diltiazem on the relationship between myocardial blood flow and regional myocardial mechanical performance was… 
Highly Cited
1975
Highly Cited
1975
Calcium Antagonists and Islet Function: I. Inhibition of Insulin Release by Verapamil
Verapamil is a potent calcium antagonist known to inhibit excitation-contraction coupling in both myocardium and myometrium. Its…