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cytidylyl-3'-5'-guanosine

Known as: CpG Dinucleotide, CG-dinucleotide, CpG 
A dinucleotide consisting of cytosine followed by guanine.
National Institutes of Health

Related topics

Related topics

3 relations
Base SequenceCpG Islands

Broader (1)

Dinucleoside Phosphates

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Cellular immunostimulation by CpG-sequence-coated DNA origami structures.
To investigate the potential of DNA origami constructs as programmable and noncytotoxic immunostimulants, we tested the immune… 
Highly Cited
2004
Highly Cited
2004
Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2).
Cytosine methylation in CpG dinucleotides is believed to be important in gene regulation, and is generally associated with… 
Highly Cited
2004
Highly Cited
2004
Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration
DNA containing unmethylated cytidyl guanosyl (CpG) sequences, which are underrepresented in mammalian genomes but prevalent in… 
Highly Cited
2003
Highly Cited
2003
Flexibility of Mouse Classical and Plasmacytoid-derived Dendritic Cells in Directing T Helper Type 1 and 2 Cell Development
Distinct dendritic cell (DC) subsets have been suggested to be preprogrammed to direct either T helper cell (Th) type 1 or Th2… 
Highly Cited
1999
Highly Cited
1999
CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression.
The molecular basis of aberrant hypermethylation of CpG islands observed in a subset of human colorectal tumors is unknown. One… 
Highly Cited
1998
Highly Cited
1998
Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA.
Genetic vaccination depends at least in part on the adjuvant properties of plasmids, properties that have been ascribed to… 
Highly Cited
1998
Highly Cited
1998
CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge.
Vertebrates have evolved innate immune defense mechanisms that recognize and respond to structural patterns that are specific to… 
Review
1995
Review
1995
CpG islands and genes.
Highly Cited
1994
Highly Cited
1994
Purification of CpG islands using a methylated DNA binding column
CpG islands are short stretches of DNA containing a high density of non–methylated CpG dinucleotides, predominantly associated… 
Highly Cited
1989
Highly Cited
1989
CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation.
In mammals and other vertebrates, cytosine methylation in CpG sites is often negatively correlated with gene activity. Because… 
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