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  • Victoria Valinluck, Hsin-hao Tsai, Daniel K. Rogstad, Artur Burdzy, Adrian Bird, Lawrence C. Sowers
  • Biology, Medicine
  • Nucleic acids research
  • 2004 (First Publication: 3 August 2004)
  • Cytosine methylation in CpG dinucleotides is believed to be important in gene regulation, and is generally associated with reduced levels of transcription. Methylation-mediated gene silencingContinue Reading
  • Jacob A. Theruvathu, Cherine H Kim, Daniel K. Rogstad, Jonathan W. Neidigh, Lawrence C. Sowers
  • Chemistry, Medicine
  • Biochemistry
  • 2009 (First Publication: 11 August 2009)
  • Inflammation-mediated reactive molecules can damage DNA by oxidation and chlorination. The biological consequences of this damage are as yet incompletely understood. In this paper, we haveContinue Reading
  • Daniel K. Rogstad, Jason L. Herring, +4 authors Lawrence C. Sowers
  • Chemistry, Medicine
  • Chemical research in toxicology
  • 2009 (First Publication: 15 June 2009)
  • The nucleoside analogue 5-aza-2'-deoxycytidine (Decitabine, DAC) is one of several drugs in clinical use that inhibit DNA methyltransferases, leading to a decrease of 5-methylcytosine in newlyContinue Reading
  • James Harris Morrison, Rebekah B Guevara, +4 authors Eric M. Poeschla
  • Biology, Medicine
  • Journal of virology
  • 2014 (First Publication: 15 March 2014)
  • UNLABELLED BST2/tetherin inhibits the release of enveloped viruses from cells. Primate lentiviruses have evolved specific antagonists (Vpu, Nef, and Env). Here we characterized tetherin proteins ofContinue Reading
  • Agus Darwanto, Alvin Farrel, Daniel K. Rogstad, Lawrence C. Sowers
  • Chemistry, Medicine
  • Analytical biochemistry
  • 2009 (First Publication: 1 November 2009)
  • The DNA of all organisms is persistently damaged by endogenous reactive molecules. Most of the single-base endogenous damage is repaired through the base excision repair (BER) pathway that isContinue Reading
  • Daniel K. Rogstad, Agus Darwanto, +5 authors Lawrence C. Sowers
  • Chemistry, Medicine
  • Chemical research in toxicology
  • 2007 (First Publication: 1 December 2007)
  • The DNA of all organisms is constantly damaged by oxidation. Among the array of damage products is 5-hydroxymethyluracil, derived from oxidation of the thymine methyl group. Previous studies haveContinue Reading