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Tumor Necrosis Factors

Known as: TNFSF Protein, Necrosis Factors, Tumor, tumor necrosis factor (unspecified) 
A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated… 
National Institutes of Health

Related topics

Related topics

40 relations
A-Tumor Necrosis Fact SerPl-mCncApoptosis Regulatory ProteinsC1QTNF8 geneCachexia

Broader (4)

Blood ProteinsCytotoxinGlycoproteinsMonokines

Narrower (4)

TASONERMINTNF protein, humanTNFSF12 protein, humanTumor Necrosis Factor-alpha

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Assay for redox-sensitive transcription factor.
Review
1998
Review
1998
The caspase-RB connection in cell death.
Review
1998
Review
1998
Cytokines produced by susceptible and resistant mice in the course of Paracoccidioides brasiliensis infection.
Paracoccidioidomycosis (PCM) is the most prevalent deep mycosis in Latin America and presents a wide spectrum of clinical… 
Highly Cited
1994
Highly Cited
1994
Concomitant in vivo production of 19 different cytokines in human tonsils.
Accumulating data indicate that cytokines, peptides involved in regulation of both physiological and pathological immune… 
Highly Cited
1990
Highly Cited
1990
Lipopolysaccharide-induced fetal resorption in mice is associated with the intrauterine production of tumour necrosis factor-alpha.
Certain strains of mice display an increased frequency of fetal resorption, but little is known about the effector mechanisms… 
Review
1990
Review
1990
Cytokine production in the rheumatoid joint: implications for treatment.
Cytokines are protein mediators that play a part in inflammation, the immune response, cell growth, repair, and fibrosis. All of… 
Highly Cited
1989
Highly Cited
1989
Macrophage activation by granulocyte/macrophage colony-stimulating factor. Priming for enhanced release of tumor necrosis factor-alpha and prostaglandin E2.
The macrophage-activating properties of murine recombinant granulocyte-macrophage (GM)-CSF were studied in murine peritoneal… 
Highly Cited
1989
Highly Cited
1989
Soluble malarial antigens are toxic and induce the production of tumour necrosis factor in vivo.
Heat-stable soluble products of rodent malarial parasites induce activated peritoneal macrophages to secrete tumour necrosis… 
Highly Cited
1988
Highly Cited
1988
Association between HLA‐DR2 and Production of Tumour Necrosis Factor α and Interleukin 1 by Mononuclear Cells Activated by Lipopolysaccharide
The production of tumour necrosis factor (TNF) and interleukin 1 (IL‐1) by lipopolysaccharide‐activated mononuclear cells from 39… 
Highly Cited
1987
Highly Cited
1987
Recombinant tumor necrosis factor causes activation of human granulocytes.
We have tested the hypothesis that tumor necrosis factor (TNF), by binding to and activating granulocytes, may contribute to the… 
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