Tumor Necrosis Factors

Known as: TNFSF Protein, Necrosis Factors, Tumor, tumor necrosis factor (unspecified) 
A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
The discovery that the tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) can induce apoptosis of cancer cells… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS Tumor necrosis factor blockade has been shown to be an effective treatment strategy in Crohn's disease (CD… (More)
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Review
1999
Review
1999
Four members of the tumor necrosis factor (TNF) ligand family, TNF-alpha, LT-alpha, LT-beta, and LIGHT, interact with four… (More)
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Highly Cited
1997
Highly Cited
1997
Tumor necrosis factor alpha (TNF alpha) is a potent immunomodulator and proinflammatory cytokine that has been implicated in the… (More)
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Highly Cited
1996
Highly Cited
1996
Cytokines in the tumor necrosis factor (TNF) family regulate development and function of the immune system. We have isolated a… (More)
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Highly Cited
1995
Highly Cited
1995
Obesity is frequently associated with insulin resistance and abnormal glucose homeostasis. Recent studies in animal models have… (More)
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Highly Cited
1995
Highly Cited
1995
Understanding the immunological mechanisms of protection and pathogenesis in tuberculosis remains problematic. We have examined… (More)
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Highly Cited
1993
Highly Cited
1993
The Fas antigen (Fas) belongs to the tumor necrosis factor (TNF)/nerve growth factor receptor family, and it mediates apoptosis… (More)
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Highly Cited
1993
Highly Cited
1993
The multiple biological activities of tumor necrosis factor (TNF) are mediated by two distinct cell surface receptors of 55 kd… (More)
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Highly Cited
1988
Highly Cited
1988
Cytokines, products of stimulated macrophages, are thought to mediate many host responses to bacterial infection, but increased… (More)
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