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Cytotoxin

Known as: Cytotoxins, cytotoxic substances, cytotoxic substance 
Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in… 
National Institutes of Health

Related topics

Related topics

21 relations
Antineoplastic AgentsCytostatic AgentsIn BloodProcess of secretion

Narrower (8)

CytolysinsGranzymesKiller Factors, YeastLeukocidins

Broader (1)

Toxin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2002
Review
2002
Telomeres and telomerases as drug targets.
Highly Cited
2000
Highly Cited
2000
Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance.
OC144-093 is a novel substituted diarylimidazole (Mr 495) generated using the OntoBLOCK system, a solid-phase combinatorial… 
Highly Cited
2000
Highly Cited
2000
TNF- α augments intratumoural concentrations of doxorubicin in TNF- α -based isolated limb perfusion in rat sarcoma models and enhances anti-tumour effects
We have shown previously that isolated limb perfusion (ILP) in sarcoma-bearing rats results in high response rates when melphalan… 
Highly Cited
1993
Highly Cited
1993
Monoclonal antibody to an external epitope of the human mdr1 P-glycoprotein.
A membrane glycoprotein, termed P-glycoprotein, has been shown to be responsible for cross-resistance to a broad range of… 
Highly Cited
1991
Highly Cited
1991
Cytotoxicity of a BIS-GMA dental composite before and after leaching in organic solvents.
Cell culture techniques were used to determine the source of cytotoxic agents in a commercial BIS-GMA composite. The material was… 
Review
1987
Review
1987
Essential synergy between Ca2+ and guanine nucleotides in exocytotic secretion from permeabilized rat mast cells
Rat mast cells, pretreated with metabolic inhibitors and permeabilized by streptolysin-O, secrete histamine when provided with… 
Review
1983
Review
1983
SCREENING OF TOXIC COMPOUNDS IN MAMMALIAN CELL CULTURES
The cytotoxic concentrations of about 100 randomly selected drugs and chemicals, tested on HeLa cells in the MIT-24 system and/or… 
Highly Cited
1983
Highly Cited
1983
Molecular mechanisms in tumor-cell killing by activated macrophages.
Highly Cited
1979
Highly Cited
1979
Acute and latent infection of sensory ganglia with herpes simplex virus: immune control and virus reactivation.
The role of antiviral antibody in controlling the acute and latent phases of herpes simplex virus (HSV) infection in sensory… 
Highly Cited
1976
Highly Cited
1976
The management of deeply infiltrating (T3) bladder carcinoma: controlled trial of radical radiotherapy versus preoperative radiotherapy and radical cystectomy (first report).
The preliminary results are presented of a multicentre, co-operative randomised trial, sponsored by the Institute of Urology… 
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