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Cytostatic Agents

Known as: Cytostatic Drugs, Cytostatics, cytostatic 
Compounds that inhibit or prevent the proliferation of CELLS.
National Institutes of Health

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7 relations
CytotoxinIn Bloodagonistsantagonists & inhibitors

Papers overview

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Highly Cited
2005
Highly Cited
2005
Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells
Purpose The ruthenium complex salt indazolium trans-[tetrachlorobisindazole-ruthenate(III)] (KP1019) and the analogous sodium… 
Highly Cited
2001
Highly Cited
2001
Linking molecular therapeutics to molecular diagnostics: Inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo
Molecular therapeutics, targeting the underlying defects leading to cancer initiation and progression, are the “holy grail” of… 
Highly Cited
1999
Highly Cited
1999
Induction of metaphase arrest in cleaving Xenopus embryos by the protein kinase p90Rsk.
Before fertilization, vertebrate eggs are arrested in metaphase of meiosis II by cytostatic factor (CSF), an activity that… 
Highly Cited
1993
Highly Cited
1993
Induction of metaphase arrest in cleaving Xenopus embryos by MAP kinase.
The natural arrest of vertebrate unfertilized eggs in second meiotic metaphase results from the activity of cytostatic factor… 
Highly Cited
1993
Highly Cited
1993
Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells.
Highly Cited
1993
Highly Cited
1993
Substrate specificity of mitochondrial 2'-deoxyguanosine kinase. Efficient phosphorylation of 2-chlorodeoxyadenosine.
Highly Cited
1989
Highly Cited
1989
Intracellular distribution and pharmacokinetics of daunorubicin in anthracycline-sensitive and -resistant HL-60 cells.
Anthracycline-sensitive (HL-60) and -resistant (HL-60/AR) cells, which do not overexpress the P-glycoprotein, each transport and… 
Review
1985
Review
1985
Occupational exposure to anticancer drug--potential and real hazards.
Highly Cited
1980
Highly Cited
1980
Role of G0-G1 arrest in the inhibition of tumor cell growth by interferon.
We report here that human leukocyte interferon preparations are capable of influencing the transition of human melanoma cells… 
Highly Cited
1965
Highly Cited
1965
QUANTITATIVE STUDIES ON THE BEHAVIOR OF SENSITIZED LYMPHOCYTES IN VITRO
The cytocidal effect of specifically sensitized lymphoid cells on homologous target cells in culture can be inhibited by small… 
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