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Granzymes

Known as: EC 3.4.21.-, Granzymes [Chemical/Ingredient], Granzyme 
A family of serine endopeptidases. Members of this family are stored in the granules of cytotoxic T cells. Upon release of the granules, these… 
National Institutes of Health

Related topics

Related topics

22 relations
Cellular ImmunityGZMA protein, humanGZMB protein, humanIn Blood

Broader (1)

Cytotoxin

Narrower (7)

GZMH protein, humanGranzyme CGranzyme KGzmc protein, mouse

Papers overview

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Review
2015
Review
2015
Early Tumor-Infiltrating Dendritic Cells Change their Characteristics Drastically in Association with Murine Melanoma Progression
This is a PDF file of an unedited peer-reviewed manuscript that has been accepted for publication. NPG are providing this early… 
2015
2015
Correction: Granule Associated Serine Proteases of Hematopoietic Cells – An Analysis of Their Appearance and Diversification during Vertebrate Evolution
2006
2006
Influence of pentoxifylline on natural cytotoxicity and expression of granzymes and PI-9, a specific granzyme B inhibitor.
Pentoxifylline (PTX) is an unspecific inhibitor of phosphodiesterase activity that increases intracellular concentration of… 
Review
2005
Review
2005
In vitro activation of CPP 32 and Mch 3 by Mch 4 , a novel human apoptotic cysteine protease containing two FADD-like domains ( granzyme B / Mch 2 / protease cascade / FAS / APO-I-receptor )
Emerging evidence suggests that an amplifiable protease cascade consisting of multiple aspartatespecific cysteine proteases… 
2004
2004
Lymphocytic gastritis in pediatric celiac disease -- immunohistochemical study of the intraepithelial lymphocytic component.
BACKGROUND Lymphocytic gastritis (LG) is defined by the recognition of >25 intraepithelial lymphocytes (IEL) per 100 surface… 
2001
2001
Death and Destruction
![Graphic][1] Aggresome (green) forming next to DNA (blue). Kopito/RUP Deposits of aggregated proteins have long been… 
2000
2000
(cid:103)(cid:100) T-Cell Lymphoma of the Skin A Clinical, Microscopic, and Molecular Study
Background: Only a few cases of primary (cid:103)(cid:100) cutaneous T-cell lymphoma (CTCL) have been reported. We encountered 3… 
1999
1999
The 5' flanking region of the human granzyme H gene directs expression to T/natural killer cell progenitors and lymphokine-activated killer cells in transgenic mice.
Human granzyme H is a neutral serine protease that is expressed predominantly in the lymphokine-activated killer (LAK)/natural… 
Review
1996
Review
1996
Activation of apoptosis pathways by granzyme B.
Cytotoxic lymphocytes induce apoptosis of target cells by degranulating and releasing the serine protease granzyme B and the pore… 
1993
1993
ENDOMYOCARDIAL BIOPSIES AFTER HEART TRANSPLANTATION: THE PRESENCE OF MARKERS INDICATIVE OF ACTIVATION
A series of 104 endomyocardial biopsies (EMB) from patients after heart transplantation was evaluated for the presence of…