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Recognition of microbial infection and initiation of host defense responses is controlled by multiple mechanisms. Toll-like… Expand The classical pathway of interferon-γ-dependent activation of macrophages by T helper 1 (TH1)-type responses is a well… Expand Induction of the adaptive immune response depends on the expression of co-stimulatory molecules and cytokines by antigen… Expand BACKGROUND
Cytomegalovirus (CMV) disease in immunocompromised patients correlates with a deficiency of CD8+ cytotoxic T… Expand Virologic and immunologic studies were performed on five patients presenting with primary human immunodeficiency virus type 1… Expand An important limitation that has emerged in the use of adenoviruses for gene therapy has been loss of recombinant gene expression… Expand CD34+ cells in human cord blood and marrow are known to give rise to dendritic cells (DC), as well as to other myeloid lineages… Expand Pregnant females are susceptible to intracellular pathogens and are biased towards humoral rather than cell-mediated immunity… Expand Tuberculosis, a major health problem in developing countries, has reemerged in recent years in many industrialized countries. The… Expand Abstract Two young unrelated girls with similar but not identical manifestations of immunological deficiency were found to have… Expand