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Antibody-Dependent Cellular Cytotoxicity

Known as: antibody-dependent cell death, Antibody-Dependent Cell Cytoxicity, Cell Cytoxicity, Antibody Dependent 
The target killing of a cell depending on antibody recognition. An antibody is directed to the target by antigen-binding arms and anchors to the… 
National Institutes of Health

Papers overview

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Review
2015
Review
2015
Natural killer (NK) cells play a major role in cancer immunotherapies that involve tumor-antigen targeting by monoclonal… 
Highly Cited
2008
Highly Cited
2008
Purpose: Lenalidomide has significant activity in myelodysplastic syndromes, multiple myeloma, and non-Hodgkin's lymphoma (NHL… 
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Highly Cited
2008
Highly Cited
2008
Currently, no approved monoclonal antibody (mAb) therapies exist for human multiple myeloma (MM). Here we characterized cell… 
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Highly Cited
2008
Highly Cited
2008
PURPOSE The anti-HER-2/neu monoclonal antibody trastuzumab has been shown to engage both activatory (fragment C receptor [Fc… 
Highly Cited
2005
Highly Cited
2005
Effector cells armed with Abs can eliminate virus-infected target cells by Ab-dependent cellular cytotoxicity (ADCC), an immune… 
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Highly Cited
2004
Highly Cited
2004
To generate industrially applicable new host cell lines for antibody production with optimizing antibody‐dependent cellular… 
Highly Cited
2004
Highly Cited
2004
Human IgG1 antibodies with low fucose contents in their asparagine-linked oligosaccharides have been shown recently to exhibit… 
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Highly Cited
2003
Highly Cited
2003
An anti-human interleukin 5 receptor (hIL-5R) humanized immunoglobulin G1 (IgG1) and an anti-CD20 chimeric IgG1 produced by rat… 
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Highly Cited
1999
Highly Cited
1999
The glycosylation pattern of chCE7, an antineuroblastoma chimeric IgG1, was engineered in Chinese hamster ovary cells with… 
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Highly Cited
1998
Highly Cited
1998
The entry of human immunodeficiency virus (HIV) into cells requires the sequential interaction of the viral exterior envelope… 
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