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Antibody-Dependent Cellular Cytotoxicity

Known as: antibody-dependent cell death, Antibody-Dependent Cell Cytoxicity, Cell Cytoxicity, Antibody Dependent 
The target killing of a cell depending on antibody recognition. An antibody is directed to the target by antigen-binding arms and anchors to the… 
National Institutes of Health

Related topics

Related topics

44 relations
Agonistic Anti-OX40 Monoclonal Antibody MEDI6383Agonistic Anti-OX40 Monoclonal Antibody MEDI6469Anti-GRP78 Monoclonal Antibody PAT-SM6Anti-Ganglioside GM2 Monoclonal Antibody BIW-8962

Papers overview

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Highly Cited
1984
Highly Cited
1984
Characteristics of human NK clones: target specificity and phenotype.
Clones derived from purified human large granular lymphocytes (LGL) of three different donors were expanded in culture medium… 
Highly Cited
1982
Highly Cited
1982
Lymphocyte mediated cytolysis as a secretory phenomenon.
In this paper we would like to develop the idea that lymphocyte-mediated killing of foreign cells is a result of a secretory… 
1981
1981
Antibody-dependent cellular cytotoxicity in recurrent aphthous ulceration.
Antibody-dependent cellular cytotoxicity (ADCC) was investigated as s possible mechanism of pathogenesis in recurrent aphthous… 
Highly Cited
1981
Highly Cited
1981
Surface markers of cloned human T cells with various cytolytic activities
Human T cells stimulated in secondary allogeneic mixed lymphocyte culture (MLC) were cloned under limiting conditions in… 
Highly Cited
1979
Highly Cited
1979
Restoration of impaired immune functions of aged animals by chronic bestatin treatment.
An attempt to correct the state of immunodeficiency in old age was made by repeatedly injecting a chemically defined… 
Highly Cited
1979
Highly Cited
1979
ADCC (K‐Cell) Lysis of Human Erythrocytes Sensitized with Rhesus Alloantibodies
Summary. The mechanism of lysis of anti‐D coated human erythrocytes by human mononuclear K‐cells was investigated. Red cell lysis… 
Highly Cited
1977
Highly Cited
1977
Lymphocytes with T-cell markers cooperate with IgG antibodies in the lysis of human tumour cells
THYMUS-DERIVED (T) lymphocytes from animals immunised with syngeneic or allogeneic tumour cells are well known to kill… 
Highly Cited
1977
Highly Cited
1977
Determination of specificity in natural cell-mediated cytotoxicity by natural antibodies.
Natural cell-mediated cytotoxicity (NCMC) and antibody-dependent cell-mediated cytotoxicity (ADCC) appeared to involve similar… 
Highly Cited
1976
Highly Cited
1976
Characterization of the target cell receptor for IgE. II. Polyacrylamide gel analysis of the surface IgE receptor from normal rat mast cells and from rat basophilic leukemia cells.
Purified rat peritoneal mast cells (RMC) and cultured rat basophilic leukemia (RBL) cells were surface labeled with 125I by using… 
Review
1976
Review
1976
The genetic and cellular basis of regulation of the immune response to tumor antigens.
In this chapter I have dealt with the cellular and genetic basis of regulation of the immune response to tumor antigen. I have… 
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