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TNFSF12 protein, human
Known as:
TNF-Related Weak Inducer of Apoptosis
, APO3/DR3 Ligand
, Tumor Necrosis Factor Ligand Superfamily Member 12
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Tumor necrosis factor ligand superfamily member 12 (249 aa, ~27 kDa) is encoded by the human TNFSF12 gene. This protein plays a role in the positive…
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National Institutes of Health
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Related topics
Related topics
17 relations
Angiogenesis Promoter
Apoptosis
Apoptosis Regulatory Proteins
Cell Death
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Broader (1)
Tumor Necrosis Factors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
TWEAK / Fn 14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier
D. Stephan
,
O. Sbai
,
+4 authors
M. Khrestchatisky
2018
Corpus ID: 53539391
Background: The TNF ligand family member TWEAK exists as membrane and soluble forms and is involved in the regulation of various…
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2017
2017
Noncanonical NF-κB Signaling in Glioma is Activated by TWEAK and Promotes Invasion
Evan Cherry
2017
Corpus ID: 89933649
2015
2015
TWEAK / Fn 14 interaction regulates RANTES production , BMP-2-induced differentiation , and RANKL expression in mouse osteoblastic MC 3 T 3E 1 cells
Takashi Ando
,
Jiro Ichikawa
,
+8 authors
A. Nakao
2015
Corpus ID: 34408890
Tumour necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK), a member of the TNF family, is a multifunctional cytokine…
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2015
2015
GrB-TWEAK: A Potential Novel Biologic for NSCLC Therapy
J. Winkles
2015
Corpus ID: 53547972
Abstract : Our laboratory research is focused on the potential roles of the TNF-related cytokine named TWEAK and its specific…
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2014
2014
FGF 1-mediated cardiomyocyte cell cycle reentry depends on the interaction of FGFR-1 and Fn 14
Tatyana Novoyatleva
,
A. Sajjad
,
D. Pogoryelov
,
Chinmoy Patra
,
R. Schermuly
,
F. Engel
2014
Corpus ID: 22384439
Fibroblast growth factors (FGFs) signal through FGF receptors (FGFRs) mediating a broad range of cellular functions during…
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2013
2013
Cancer Therapy : Preclinical RG 7212 Anti-TWEAK mAb Inhibits Tumor Growth through Inhibition of Tumor Cell Proliferation and Survival Signaling and by Enhancing the Host Antitumor Immune Response
Xuefeng Yin
,
Leopoldo L. Luistro
,
+18 authors
M. Simcox
2013
Corpus ID: 37600753
Purpose:Toexplore the role of TWEAK in tumor growthandantitumor immune response and the activity and mechanism of RG7212, an…
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2010
2010
Tumor Necrosis Factor ( TNF ) Signaling , but Not TWEAK ( TNF-like Weak Inducer of Apoptosis )-triggered cIAP 1 ( Cellular Inhibitor of Apoptosis Protein 1 ) Degradation , Requires cIAP 1 RING…
R. Feltham
,
M. Moulin
,
+6 authors
J. Silke
2010
Corpus ID: 2033737
Cellular inhibitor of apoptosis (cIAP) proteins, cIAP1 and cIAP2, are important regulators of tumor necrosis factor (TNF…
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2008
2008
Involvement of TWEAK / Fn 14 interaction in the synovial inflammation of
Ra
,
S. Kamijo
,
+4 authors
K. Okumura
2008
Corpus ID: 121159102
Objective. TWEAK, TNF-like weak inducer of apoptosis, induces not only apoptosis of some tumour cells, but also proliferation of…
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2004
2004
Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells
原田 紀宏
2004
Corpus ID: 87183290
2004
2004
Involvement of GSK-3 b in TW EAK-mediated NF-j B activation
Adelheid De Ketelaerea
,
Linda Vermeulenb
,
+4 authors
Inge Moelansa
2004
Corpus ID: 189811496
Glycogen synthase kinase-3b (GSK-3b) is a key component of several signaling pathways. We found that a short variant of ‘TNF-like…
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