TNF protein, human

Known as: TNF-A, TNFSF2 protein, human, TNF-2 protein, human 
Tumor necrosis factor (233 aa, ~26 kDa) is encoded by the human TNF gene. This protein is involved in the induction of cytokine expression, the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2017
0102019862017

Papers overview

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Highly Cited
2009
Highly Cited
2009
Oxidative stresses are believed to play an important role in the induction of both cell adhesion molecules and pro-inflammatory… (More)
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2008
2008
We examined whether Siglec-9 modulates cytokine production in the macrophage cell line RAW264. Cells expressing Siglec-9 produced… (More)
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Highly Cited
2002
Highly Cited
2002
The cellular redox state regulates nuclear factor-kappaB (NF-kappaB) signaling systems. We investigated the effects of H2O2 on… (More)
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2002
2002
OBJECTIVE The mechanisms by which monocyte/macrophage cells migrate to the joint involve a series of integrated adhesion and… (More)
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Highly Cited
1997
Highly Cited
1997
Tumor necrosis factor alpha (TNF alpha) is a potent immunomodulator and proinflammatory cytokine that has been implicated in the… (More)
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Highly Cited
1997
Highly Cited
1997
Cross-coupling of active protein-1 (AP-1) and nuclear factor (NF)-kappaB has been reported. In the present study, we investigated… (More)
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Highly Cited
1993
Highly Cited
1993
To probe the ligand receptor interface, a number of point mutations were introduced in selected regions of human tumor necrosis… (More)
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Highly Cited
1990
Highly Cited
1990
Two proteins which specifically bind tumor necrosis factor (TNF) have recently been isolated from human urine in our laboratory… (More)
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1987
1987
Highly purified recombinant human tumor necrosis factor (TNF) was found to induce interleukin 1 (IL 1) production in diploid… (More)
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1986
1986
We report that tumor necrosis factor (TNF) provokes superoxide anion generation from human neutrophils. Superoxide anion… (More)
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