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Apoptosis Promoter

Known as: Inducer of Apoptosis 
A protein that promotes the initiation, progress, or rate of apoptosis.
National Institutes of Health

Related topics

Related topics

43 relations
APAF1 protein, humanApoptosisApoptosis Regulatory ProteinsBCL-Xs protein
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Papers overview

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2014
2014
2-Hydroxyethyl methacrylate-induced apoptosis through the ATM- and p53-dependent intrinsic mitochondrial pathway.
Resin monomers of dental composites like 2-hydroxyethyl methacrylate (HEMA) disturb cell functions including responses of the… Expand
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Highly Cited
2012
Highly Cited
2012
Caspase levels and execution efficiencies determine the apoptotic potential of the cell
Differences in expression level of the effector caspases Drice and Dcp-1 and in their intrinsic abilities to induce apoptosis and… Expand
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2012
2012
Effects of Activin and TGFβ on p21 in Colon Cancer
Activin and TGFβ share SMAD signaling and colon cancers can inactivate either pathway alone or simultaneously. The differential… Expand
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Highly Cited
2010
Highly Cited
2010
The small 11 kDa nonstructural protein of human parvovirus B19 plays a key role in inducing apoptosis during B19 virus infection of primary erythroid progenitor cells.
Human parvovirus B19 (B19V) infection shows a strong erythroid tropism and drastically destroys erythroid progenitor cells, thus… Expand
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2008
2008
Noscapine induces apoptosis in human glioma cells by an apoptosis-inducing factor-dependent pathway
Previously, we identified noscapine as a small molecule inhibitor of the hypoxia-inducible factor-1 pathway in hypoxic human… Expand
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2006
2006
The oxidized phospholipids POVPC and PGPC inhibit growth and induce apoptosis in vascular smooth muscle cells.
Oxidized phospholipids, including 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphocholine (POVPC) and 1-palmitoyl-2-glutaroyl… Expand
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Highly Cited
2000
Highly Cited
2000
c-Jun-Dependent CD95-L Expression Is a Rate-Limiting Step in the Induction of Apoptosis by Alkylating Agents
ABSTRACT Mouse 3T3 fibroblasts derived from fetuses lacking c-Jun were used to define an essential role of c-Jun, a main… Expand
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2000
2000
Abundance of cyclin B1 regulates gamma-radiation-induced apoptosis.
gamma-Radiation is a potent inducer of apoptosis. There are multiple pathways regulating DNA damage-induced apoptosis, and we set… Expand
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Highly Cited
1995
Highly Cited
1995
Expression of members of the bcl-2 gene family in the immature rat ovary: equine chorionic gonadotropin-mediated inhibition of granulosa cell apoptosis is associated with decreased bax and…
The loss of ovarian follicles through atresia, which accounts for greater than 99% of postnatal female germ cell depletion, is… Expand
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Review
1994
Review
1994
Integrated control of cell proliferation and cell death by the c-myc oncogene.
Regulation of multicellular architecture involves a dynamic equilibrium between cell proliferation, differentiation with… Expand
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