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APAF1 protein, human
Known as:
APAF1 Protein
, Apoptotic Protease Activating Factor 1
, apoptotic protease activating factor, human
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Apoptotic protease-activating factor 1 (1248 aa, ~142 kDa) is encoded by the human APAF1 gene. This protein plays a role in protein-protein…
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National Institutes of Health
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Related topics
Related topics
14 relations
APAF1 gene
Alzheimer's Disease Pathway KEGG
Apoptosis
Apoptosis Promoter
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Broader (1)
apoptotic protease-activating factor 1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Effects of sodium alendronate on osteoporosis and apoptosis-related factors Cyt C, Apaf-1 and caspase-9
Hong Li
,
Chun-de Li
,
X. Yi
,
Hong Liu
,
Yu Wang
2018
Corpus ID: 55054548
Objective: To investigate the clinical effect of alendronate on osteoporosis and its effect on Cyt C, Apaf-1 and caspase-9…
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2015
2015
5-Aza-2'-Deoxycytidine and CDDP Synergistically Induce Apoptosis in Renal Carcinoma Cells via Enhancing the APAF-1 Activity.
Xiaojun Zhu
,
Faxian Yi
,
+4 authors
Wanlong Tan
Clinical Laboratory
2015
Corpus ID: 22692301
BACKGROUND It has been reported that the hypermethylation of APAF-1, DAPK-1 and other tumor suppressive genes (TSGs) correlates…
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Review
2011
Review
2011
CASP-9 (caspase 9, apoptosis-related cysteine peptidase)
F. Cecconi
,
S. Bartolomeo
2011
Corpus ID: 33191453
Review on CASP-9 (caspase 9, apoptosis-related cysteine peptidase), with data on DNA, on the protein encoded, and where the gene…
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2010
2010
Proteomic analysis for the anti‐apoptotic effects of cystamine on apoptosis‐prone macrophage
Shao-Hsuan Kao
,
T. Hsu
,
+4 authors
B. Tzang
Journal of Cellular Biochemistry
2010
Corpus ID: 27790424
Increased macrophage vulnerability is associated with progression of systemic lupus erythematosus. Our previous studies have…
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2007
2007
Apoptosis as a therapeutic target in heart failure.
Manika Das
American Journal of Physiology. Heart and…
2007
Corpus ID: 7577104
heart failure, the ultimatum of various forms of myocardial disease, is associated with high mortality rate in this modern world…
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2007
2007
Dihydrodiol dehydrogenase in drug resistance and sensitivity of human carcinomas
B. Pan
,
J. Arly Nelson
Cancer Chemotherapy and Pharmacology
2007
Corpus ID: 30427355
We previously reported (UroOncology 1:165, 2001) cross-resistance and collateral-sensitivity to 2-chlorodeoxyadenosine (CldAdo…
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Review
2005
Review
2005
E2F and p53 make a nice couple: converging pathways in apoptosis
B. Dynlacht
Cell Death and Differentiation
2005
Corpus ID: 2979664
It has been known for some time that p53 activation elicits growth arrest in normal cells, whereas activation of this tumor…
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2002
2002
Genomic plasticity in cell death susceptibility
J. Pru
,
J. Tilly
Cell Death and Differentiation
2002
Corpus ID: 26446901
Cross-species comparisons of the intracellular machinery responsible for regulating and executing cell death have revealed…
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2001
2001
APAF 1 is a key transcriptional target for p 53 in the regulation of neuronal cell death
A. Fortin
,
S. Cregan
,
+9 authors
R. Slack
2001
Corpus ID: 20805987
53 is a transcriptional activator which has been implicated as a key regulator of neuronal cell death after acute injury. We have…
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2001
2001
Insight into age-related macular degeneration: New vision in sight
C. Richter
Cell Death and Differentiation
2001
Corpus ID: 9725187
Age-related macular degeneration (AMD) affects 10 ± 20% of people at an age over 65 and constitutes one of the leading causes of…
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