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Apoptosis

Known as: Mechanism that allows cells to self-destruct when it is necessary, Programmed Cell Death, Type I, Programmed Cell Death 
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death… 
National Institutes of Health

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Related topics

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AATF geneADRA1A protein, humanAGTR2 geneANP32B wt Allele

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Apoptosis, Extrinsic Pathway

Papers overview

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Highly Cited
2004
Highly Cited
2004
Genome-wide discovery of loci influencing chemotherapy cytotoxicity.
Little is known about the heritability of chemotherapy activity or the identity of genes that may enable the individualization of… 
Review
2002
Review
2002
Mitochondria: regulating the inevitable.
Highly Cited
2001
Highly Cited
2001
Role of oxidative stress in the apoptotic cell death of cultured cerebellar granule neurons
When cultured cerebellar granule neurons (CGN) are transferred from 25 mM KCl (K25) to 5 mM KCl (K5) caspase‐3 and caspase‐8, but… 
Review
2000
Review
2000
Higher Levels of Organization in the Interphase Nucleus of Cycling and Differentiated Cells
SUMMARY The review examines the structured organization of interphase nuclei using a range of examples from the plants, animals… 
Highly Cited
1995
Highly Cited
1995
A serine protease inhibitor, protease nexin I, rescues motoneurons from naturally occurring and axotomy-induced cell death.
Protease nexin I (PNI) is a member of the family of serine protease inhibitors (serpins) that have been shown to promote neurite… 
Highly Cited
1995
Highly Cited
1995
Defective TCR-mediated signaling in anergic T cells.
Extrathymic T cell tolerance to Ags can be achieved through clonal deletion by activation-induced programmed cell death as well… 
Highly Cited
1994
Highly Cited
1994
Programmed cell death: a fundamental protective response to pathogens.
Review
1994
Review
1994
Pharmacological inhibition of programmed lymphocyte death.
Highly Cited
1991
Highly Cited
1991
The spontaneous apoptotic cell death of normal human lymphocytes in vitro: the release of, and immunoproliferative response to, nucleosomes in vitro.
Highly Cited
1991
Highly Cited
1991
Nucleosomes occurring in protein‐free hybridoma cell culture Evidence for programmed cell death
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