Apoptosis

Known as: Mechanism that allows cells to self-destruct when it is necessary, Programmed Cell Death, Type I, Programmed Cell Death 
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death… (More)

Topic mentions per year

Topic mentions per year

1952-2017
02000400019522016

Papers overview

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Review
2015
Review
2015
Plant secondary metabolites carry out numerous functions in interactions between plants and a broad range of other organisms… (More)
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Highly Cited
2005
Highly Cited
2005
In animals, cells are dependent on extracellular signals to prevent apoptosis. However, using growth factor-dependent cells from… (More)
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Highly Cited
2002
Highly Cited
2002
Poly(ADP-ribose) polymerase-1 (PARP-1) protects the genome by functioning in the DNA damage surveillance network. PARP-1 is also… (More)
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Highly Cited
2000
Highly Cited
2000
Apoptosis, or cellular suicide, is important for normal development and tissue homeostasis, but too much or too little apoptosis… (More)
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Highly Cited
1999
Highly Cited
1999
Mitochondria play a key part in the regulation of apoptosis (cell death). Their intermembrane space contains several proteins… (More)
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Highly Cited
1997
Highly Cited
1997
Inhibitors of programmed cell death (apoptosis) aberrantly prolonging cell viability may contribute to cancer1 by facilitating… (More)
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Highly Cited
1997
Highly Cited
1997
The inactivation of the p53 gene in a large proportion of human cancers has inspired an intense search for the encoded protein's… (More)
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Highly Cited
1995
Highly Cited
1995
The protease responsible for the cleavage of poly(ADP-ribose) polymerase and necessary for apoptosis has been purified and… (More)
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Highly Cited
1994
Highly Cited
1994
Apoptosis, or programmed cell death, is a general mechanism for removal of unwanted cells from the immune system. It is… (More)
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Highly Cited
1993
Highly Cited
1993
Bcl-2 inhibits most types of apoptotic cell death, implying a common mechanism of lethality. Bcl-2 is localized to intracellular… (More)
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