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BCL-Xs protein

Known as: BCL2-Like 1, Short Isoform, Bcl-X(S), bcl-Xshort Protein 
A pro-apoptotic protein that is the short isoform of Bcl-X protein. Bcl-XS lacks the BH1 and BH2 domains of BCL-XL PROTEIN and it inhibits the ANTI… 
National Institutes of Health

Related topics

Related topics

13 relations
ApoptosisApoptosis PromoterBCL-XL ProteinBCL2L1 gene

Broader (2)

Proto-Oncogene Proteinsbcl-x protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Induction of Noxa Sensitizes Human Colorectal Cancer Cells Expressing Mcl-1 to the Small-Molecule Bcl-2/Bcl-xL Inhibitor, ABT-737
Purpose: The intrinsic drug resistance of colorectal cancers is related in part to overexpression of prosurvival Bcl-2 family… 
Highly Cited
2006
Highly Cited
2006
The preconditioning modified neuronal expression of apoptosis-related proteins of Bcl-2 superfamily following severe hypobaric hypoxia in rats
Highly Cited
2005
Highly Cited
2005
GCN5: a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes.
Highly Cited
2004
Highly Cited
2004
Breast Cancer Cells Can Evade Apoptosis-Mediated Selective Killing by a Novel Small Molecule Inhibitor of Bcl-2
Proteins of the Bcl-2 family are key regulators of caspase activation and apoptosis. Some members of this family, notably Bcl-2… 
Highly Cited
2002
Highly Cited
2002
Bcl-2/bcl-xL Bispecific Antisense Treatment Sensitizes Breast Carcinoma Cells to Doxorubicin, Paclitaxel and Cyclophosphamide
Overexpression of the anti-apoptotic proteins bcl-2 and bcl-xL is implicated in breast cancer development, tumor progression and… 
Highly Cited
1999
Highly Cited
1999
Induction of Bcl-xL Expression by Human T-Cell Leukemia Virus Type 1 Tax through NF-κB in Apoptosis-Resistant T-Cell Transfectants with Tax
ABSTRACT Human T-cell leukemia virus type 1 (HTLV-1) Tax is thought to play a pivotal role in immortalization of T cells. We have… 
Highly Cited
1999
Highly Cited
1999
Subcellular distribution and redistribution of Bcl-2 family proteins in human leukemia cells undergoing apoptosis.
It has been suggested that the ratio of Bcl-2 family proapoptotic proteins to antiapoptotic proteins determines the sensitivity… 
Highly Cited
1998
Highly Cited
1998
Expression of apoptosis regulators in cutaneous malignant melanoma.
Metastatic malignant melanoma (MM) is usually incurable and responds poorly to chemotherapy. Because many cytotoxic drugs cause… 
Highly Cited
1996
Highly Cited
1996
Type I Insulin-like Growth Factor Receptor Activation Regulates Apoptotic Proteins*
Activation of the type I insulin-like growth factor receptor (IGF-IR) blocks osmotic mediated programmed cell death (PCD) in… 
Highly Cited
1970
Highly Cited
1970
Fluorometric assay of histamine in tissues and body fluids: Choice of the purification procedure and identification in the nanogram range
ZusammenfassungVerschiedene Isolierungsverfahren für Histamin zur fluorimetrischen Bestimmung wurden geprüft. Für Histamingehalte… 
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