Skip to search formSkip to main contentSkip to account menu

BCL-Xs protein

Known as: BCL2-Like 1, Short Isoform, Bcl-X(S), bcl-Xshort Protein 
A pro-apoptotic protein that is the short isoform of Bcl-X protein. Bcl-XS lacks the BH1 and BH2 domains of BCL-XL PROTEIN and it inhibits the ANTI… 
National Institutes of Health

Related topics

Related topics

13 relations
ApoptosisApoptosis PromoterBCL-XL ProteinBCL2L1 gene

Broader (2)

Proto-Oncogene Proteinsbcl-x protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Bcl‐2 and Bcl‐xL play important roles in the crosstalk between autophagy and apoptosis
Autophagy and apoptosis play important roles in the development, cellular homeostasis and, especially, oncogenesis of mammals… 
Review
2007
Review
2007
Cell survival, cell death and cell cycle pathways are interconnected: implications for cancer therapy.
Highly Cited
2001
Highly Cited
2001
Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression.
Large granular lymphocyte (LGL) leukemia is characterized by the expansion of antigen-activated cytotoxic T lymphocytes. These… 
Highly Cited
2000
Highly Cited
2000
Blockade of the Bcr-Abl Kinase Activity Induces Apoptosis of Chronic Myelogenous Leukemia Cells by Suppressing Signal Transducer and Activator of Transcription 5–Dependent Expression of Bcl-XL
Bcr-Abl–expressing leukemic cells are highly resistant to apoptosis induced by chemotherapeutic drugs. Although a number of… 
Highly Cited
1999
Highly Cited
1999
Tumor Necrosis Factor Induces Bcl-2 and Bcl-x Expression through NFκB Activation in Primary Hippocampal Neurons*
Emerging data indicate that tumor necrosis factor (TNF) exerts a neuroprotective effect in response to brain injury. Here we… 
Highly Cited
1997
Highly Cited
1997
Interaction of CED-4 with CED-3 and CED-9: A Molecular Framework for Cell Death
Previous genetic studies of the nematode Caenorhabditis elegans identified three important components of the cell death machinery… 
Highly Cited
1997
Highly Cited
1997
A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak.
The Bcl-2 protein family is characterized by the ability to modulate cell death, and members of this family share two highly… 
Highly Cited
1996
Highly Cited
1996
Interleukin‐2 receptor common γ‐chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: Selective induction of anti‐apoptotic (bcl‐2, bcl‐xL) but not…
Cytokine deprivation from activated T cells leads to apoptosis associated with down‐regulation of the bcl‐2 gene product. It is… 
Review
1996
Review
1996
The cell-death machine
Review
1995
Review
1995
Regulation of lymphocyte survival by the bcl-2 gene family.
The control of cell survival is of central importance in tissues with high cell turnover such as the lymphoid system, and its… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)