Apoptosis Regulatory Proteins

Known as: Apoptosis Regulatory Proteins [Chemical/Ingredient], Regulator of Apoptosis, Regulatory Proteins, Apoptosis 
A large group of proteins that control APOPTOSIS. This family of proteins includes many ONCOGENE PROTEINS as well as a wide variety of classes of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The disturbance of apoptosis molecular signaling pathways is involved in carcinogenesis. BCL2 family of proteins is the hallmark… (More)
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Highly Cited
2011
Highly Cited
2011
Here, we show that tamoxifen resistance is induced by cancer-associated fibroblasts (CAFs). Coculture of estrogen receptor… (More)
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Highly Cited
2011
Highly Cited
2011
Ginsenosides are the main bioactive components in American ginseng, a commonly used herb. In this study, we showed that the… (More)
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Highly Cited
2008
Highly Cited
2008
Programmed cell death through apoptosis plays an essential role in the hormone-regulated physiological turnover of mammary tissue… (More)
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Highly Cited
2006
Highly Cited
2006
Bcl-2 is a key apoptosis regulatory protein of the mitochondrial death pathway whose function is dependent on its expression… (More)
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Highly Cited
2003
Highly Cited
2003
AbstractThe Drosophila spinster (spin) gene product is required for programmed cell death in the nervous and reproductive systems… (More)
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Highly Cited
2000
Highly Cited
2000
Two major pathways for induction of apoptosis have been identified-intrinsic and extrinsic. The extrinsic pathway is represented… (More)
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Highly Cited
2000
Highly Cited
2000
We are interested in the cytotoxic and proinflammatory effects of particulate pollutants in the respiratory tract. We demonstrate… (More)
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Highly Cited
1998
Highly Cited
1998
Metastatic malignant melanoma (MM) is usually incurable and responds poorly to chemotherapy. Because many cytotoxic drugs cause… (More)
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1996
1996
PURPOSE The tumor suppressor gene (TSG) p53 and the proto-oncogene bcl-2 have been shown to be involved in the regulation of cell… (More)
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