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Apoptosis Regulatory Proteins

Known as: Apoptosis Regulatory Proteins [Chemical/Ingredient], Regulator of Apoptosis, Regulatory Proteins, Apoptosis 
A large group of proteins that control APOPTOSIS. This family of proteins includes many ONCOGENE PROTEINS as well as a wide variety of classes of… 
National Institutes of Health

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AATF protein, humanAKTIP protein, humanAPI5 protein, humanBBC3 protein, human
ApoptosisApoptosis InhibitorApoptosis PromoterCD137 antigen

Papers overview

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Highly Cited
2019
Highly Cited
2019
Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal
Doxorubicin (Dox), an antitumor antibiotic, has therapeutic effects on many kinds of tumors. However, Dox can produce some… 
Highly Cited
2018
Highly Cited
2018
Wnt Signaling Activates TP53-Induced Glycolysis and Apoptosis Regulator and Protects Against Cisplatin-Induced Spiral Ganglion Neuron Damage in the Mouse Cochlea.
AIMS Cisplatin can damage spiral ganglion neurons (SGNs) and cause sensorineural hearing loss. Wnt activation protects against… 
Highly Cited
2011
Highly Cited
2011
Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells
Here, we show that tamoxifen resistance is induced by cancer-associated fibroblasts (CAFs). Coculture of estrogen receptor… 
Highly Cited
2009
Highly Cited
2009
Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer
IntroductionProgrammed cell death through apoptosis plays an essential role in the hormone-regulated physiological turnover of… 
Highly Cited
2009
Highly Cited
2009
Structural and Biochemical Studies of TIGAR (TP53-induced Glycolysis and Apoptosis Regulator)*
Activation of the p53 tumor suppressor by cellular stress leads to variable responses ranging from growth inhibition to apoptosis… 
Highly Cited
2008
Highly Cited
2008
Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory.
Highly Cited
2007
Highly Cited
2007
Design, synthesis, and characterization of a potent, nonpeptide, cell-permeable, bivalent Smac mimetic that concurrently targets both the BIR2 and BIR3 domains in XIAP.
XIAP is a central apoptosis regulator that inhibits apoptosis by binding to and inhibiting the effectors caspase-3/-7 and an… 
Highly Cited
1998
Highly Cited
1998
WD-40 Repeat Region Regulates Apaf-1 Self-association and Procaspase-9 Activation*
The casp9 protein plays a critical role in apoptosis induced by a variety of death stimuli. A regulator of apoptosis, Apaf-1… 
Highly Cited
1998
Highly Cited
1998
Expression of apoptosis regulators in cutaneous malignant melanoma.
Metastatic malignant melanoma (MM) is usually incurable and responds poorly to chemotherapy. Because many cytotoxic drugs cause… 
Highly Cited
1996
Highly Cited
1996
Elevated levels of apoptosis regulator proteins p53 and bcl-2 are independent prognostic biomarkers in surgically treated clinically localized prostate cancer.
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