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Tumor Necrosis Factor-alpha

Known as: Cachectin Tumor Necrosis Factor, Tumor Necrosis Factor-alpha [Chemical/Ingredient], Tumor Necrosis Factor alpha 
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines… Expand
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Obesity is characterized by increased storage of fatty acids in an expanded adipose tissue mass and is closely associated with… Expand
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Highly Cited
2003
Highly Cited
2003
Adiponectin is a 29-kDa adipocyte protein that has been linked to the insulin resistance of obesity and lipodystrophy. To better… Expand
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Review
2001
Review
2001
The authors regret the inability to cite all of the primary literature contributing to this review due to length considerations… Expand
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Highly Cited
1996
Highly Cited
1996
Tumor necrosis factor-α (TNF-α) is an important mediator of insulin resistance in obesity and diabetes through its ability to… Expand
Highly Cited
1995
Highly Cited
1995
Obesity is frequently associated with insulin resistance and abnormal glucose homeostasis. Recent studies in animal models have… Expand
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Highly Cited
1994
Highly Cited
1994
BACKGROUND AND PURPOSE Tumor necrosis factor-alpha (TNF-alpha) is a cytokine with diverse proinflammatory actions, including… Expand
Highly Cited
1993
Highly Cited
1993
Tumor necrosis factor-alpha (TNF-alpha) has been shown to have certain catabolic effects on fat cells and whole animals. An… Expand
Highly Cited
1993
Highly Cited
1993
OBJECTIVE To evaluate the safety and efficacy of a chimeric monoclonal antibody to tumor necrosis factor alpha (TNF alpha) in the… Expand
Highly Cited
1991
Highly Cited
1991
BACKGROUND Cachectin, or tumor necrosis factor-alpha (TNF-alpha), is a principal mediator of the inflammatory response and may be… Expand
Highly Cited
1989
Highly Cited
1989
Tumor necrosis factor alpha (TNF-alpha), also known as cachectin, was demonstrated to induce the expression of human… Expand