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Tumor Necrosis Factor-alpha

Known as: Cachectin Tumor Necrosis Factor, Tumor Necrosis Factor-alpha [Chemical/Ingredient], Tumor Necrosis Factor alpha 
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines… Expand
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Adiponectin is a 29-kDa adipocyte protein that has been linked to the insulin resistance of obesity and lipodystrophy. To better… Expand
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Highly Cited
2001
Highly Cited
2001
Adipose tissue expresses tumor necrosis factor (TNF) and interleukin (IL)-6, which may cause obesity-related insulin resistance… Expand
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Highly Cited
1998
Highly Cited
1998
Tumor necrosis factor-alpha (TNF-alpha) is a major mediator of both acute and chronic inflammatory responses in many diseases… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND AND PURPOSE Tumor necrosis factor-alpha (TNF-alpha) is a pleiotropic cytokine that rapidly upregulates in the brain… Expand
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Review
1996
Review
1996
Tumor necrosis factor (TNF) and lymphotoxin-α were isolated more than 10 years ago, on the basis of their ability to kill tumor… Expand
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Highly Cited
1996
Highly Cited
1996
In the present study, it was shown that physiologically relevant levels of the proinflammatory cytokine TNFalpha induced… Expand
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Highly Cited
1995
Highly Cited
1995
Obesity is frequently associated with insulin resistance and abnormal glucose homeostasis. Recent studies in animal models have… Expand
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Highly Cited
1993
Highly Cited
1993
Tumor necrosis factor-alpha (TNF-alpha) has been shown to have certain catabolic effects on fat cells and whole animals. An… Expand
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Review
1992
Review
1992
Tumor necrosis factor (TNF) came to birth in a strange way. It made its entry into the world of biology and medicine when Lloyd… Expand
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Highly Cited
1985
Highly Cited
1985
A highly specific polyclonal rabbit antiserum directed against murine cachectin/tumor necrosis factor (TNF) was prepared. When… Expand
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