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G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the physiological functions of the catecholaminergic… Expand The diverse physiological actions of dopamine are mediated by at least five distinct G protein-coupled receptor subtypes. Two D1… Expand Dopamine has been implicated in the cognitive process of working memory but the cellular basis of its action has yet to be… Expand DOPAMINE receptors belong to the family of G protein-coupled receptors. On the basis of the homology between these receptors… Expand OBJECTIVE
The initial hypothesis that schizophrenia is a manifestation of hyperdopaminergia has recently been faulted. However… Expand The striatum, which is the major component of the basal ganglia in the brain, is regulated in part by dopaminergic input from the… Expand A dopamine receptor has been characterized which differs in its pharmacology and signalling system from the D1 or D2 receptor and… Expand Pharmacological and biochemical criteria can be used to separate those dopamine receptors which are linked to the enzyme adenylyl… Expand ANTIPSYCHOTIC drugs, or neuroleptics, are thought to act by blocking dopamine receptors in the nervous system1–4. Recent direct… Expand Tritiated haloperidol and tritiated dopamine label postsynaptic dopamine receptors in mammalian brain. Clinical potencies of… Expand