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Dopamine Receptor

Known as: Receptors, Dopamine, Dopamine Receptors, Receptors, Dopamine [Chemical/Ingredient] 
A family of G protein-coupled receptors where dopamine is the primary ligand. These receptors are involved in neuroendocrine signaling.
National Institutes of Health

Related topics

Related topics

23 relations
CALY geneDopamineG Protein-Coupled Receptor GenesG Protein-Coupled Receptor Signaling

Broader (2)

Catecholamine ReceptorsNeurotransmitter Receptor

Narrower (7)

DopR protein, DrosophilaDopamine D1 ReceptorDopamine D2 Receptordopamine D3 receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1998
Highly Cited
1998
Locomotor Activity in D2 Dopamine Receptor-Deficient Mice Is Determined by Gene Dosage, Genetic Background, and Developmental Adaptations
Locomotor activity is a polygenic trait that varies widely among inbred strains of mice (Flint et al., 1995). To characterize the… 
Highly Cited
1997
Highly Cited
1997
Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity.
The benzamide derivative amisulpride shows a unique therapeutic profile being antipsychotic, at high doses, and disinhibitory, at… 
Highly Cited
1992
Highly Cited
1992
Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects.
Positron emission tomography and selective radioligands were used to determine D1 and D2 dopamine receptor occupancy induced by… 
Review
1992
Review
1992
Dopamine receptor sequences. Therapeutic levels of neuroleptics occupy D2 receptors, clozapine occupies D4.
Dopamine (DA) D2, D3, and D4 receptors are targets for antipsychotic drugs. The recent cloning, deoxyribonucleic acid sequencing… 
Highly Cited
1990
Highly Cited
1990
Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization- receptor autoradiographic analysis
Several lines of evidence suggest the existence of multiple dopamine receptor subtypes, referred to as D1 and D2. The present… 
Highly Cited
1990
Highly Cited
1990
Cloning and expression of human and rat Dt dopamine receptors
THE importance of the dopaminergic system in brain function has been emphasized by its association with neurological and… 
Highly Cited
1988
Highly Cited
1988
Central D2-dopamine receptor occupancy in schizophrenic patients treated with antipsychotic drugs.
Using positron emission tomography and the carbon 11-labeled ligand raclopride, central D2-dopamine receptor occupancy in the… 
Highly Cited
1981
Highly Cited
1981
Opposing roles for D-1 and D-2 dopamine receptors in efflux of cyclic AMP from rat neostriatum
Two types of dopamine receptor whose stimulation affects cellular cyclic AMP have now been identified. In tissues as different as… 
Highly Cited
1980
Highly Cited
1980
Haloperidol-induced catalepsy is mediated by postsynaptic dopamine receptors
Antipsychotic or neuroleptic drugs, which block central dopamine receptors, produce a behavioural state in animals in which they… 
Highly Cited
1977
Highly Cited
1977
Dopamine receptor binding enhancement accompanies lesion-induced behavioral supersensitivity.
The binding of [3H]haloperidol to rat striatal dopamine receptors increases after lesion (made by injection of 6-hydroxydopamine… 
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