Dopamine Receptor

The basal ganglia are a chain of subcortical nuclei that facilitate action selection. Two striatal projection systems--so-called… (More)

Dopamine shapes a wide variety of psychomotor functions. This is mainly accomplished by modulating cortical and thalamic… (More)

Although changes in nucleotide sequence affecting the composition and the structure of proteins are well known, functional… (More)

The diverse physiological actions of dopamine are mediated by at least five distinct G protein-coupled receptor subtypes. Two D1… (More)

Dopamine has been implicated in the cognitive process of working memory but the cellular basis of its action has yet to be… (More)

A novel mechanism for regulating dopamine activity in subcortical sites and its possible relevance to schizophrenia is proposed… (More)

The striatum, which is the major component of the basal ganglia in the brain, is regulated in part by dopaminergic input from the… (More)

Pharmacological and biochemical criteria can be used to separate those dopamine receptors which are linked to the enzyme adenylyl… (More)

Tritiated haloperidol and tritiated dopamine label postsynaptic dopamine receptors in mammalian brain. Clinical potencies of… (More)

ANTIPSYCHOTIC drugs, or neuroleptics, are thought to act by blocking dopamine receptors in the nervous system1–4. Recent direct… (More)