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G Protein-Coupled Receptor Signaling

Known as: G Protein Coupled Receptor Signaling, G-Protein Coupled Receptor Signaling, GPCR Signaling 
A cellular process that initiates with the binding of a G protein-associated transmembrane receptor to its cognate ligand,and results in a specific… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
It is well recognized that G-protein-coupled receptors (GPCRs) can activate Ras-regulated kinase pathways to produce lasting… Expand
Review
2016
Review
2016
Regulators of G protein signaling (RGS) proteins provide timely termination of G protein‐coupled receptor (GPCR) responses… Expand
Review
2016
Review
2016
G-protein coupled receptors (GPCRs), the largest family of human membrane proteins, mediate cellular signaling and represent… Expand
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Review
2013
Review
2013
G-protein coupled receptors (GPCRs) are one of the largest families of membrane receptors in eukaryotes. Heterotrimeric G… Expand
2012
2012
It has been nearly a century since Otto Loewi discovered that acetylcholine (ACh) release from the vagus produces bradycardia and… Expand
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Highly Cited
2011
Highly Cited
2011
Different patterns of GPCR phosphorylation produce distinct conformations of β-arrestin and specific downstream responses… Expand
Highly Cited
2010
Highly Cited
2010
σ Ligands modulate opioid actions in vivo, with agonists diminishing morphine analgesia and antagonists enhancing the response… Expand
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Highly Cited
2008
Highly Cited
2008
Dopamine and other G protein-coupled receptors (GPCRs) represent the major target of antipsychotic drugs. GPCRs undergo… Expand
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Review
2006
Review
2006
Specificity of transduction events is controlled at the molecular level by scaffold, anchoring, and adaptor proteins, which… Expand
Highly Cited
1997
Highly Cited
1997
G protein-coupled receptors (GPCR) represent the single most important drug targets for medical therapy, and information from… Expand
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