Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Desipramine Hydrochloride

Known as: Desipramine Hydrochloride [Chemical/Ingredient], Hydrochloride, Desipramine, desipramine hcl 
The hydrochloride salt form of desipramine, a secondary amine tricyclic antidepressant (TCA). In the central nervous system (CNS), desipramine… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
BACKGROUND There is substantial evidence that antidepressant medications treat moderate to severe depression effectively, but… Expand
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
We showed previously that cAMP response element-binding protein (CREB) within the nucleus accumbens (NAc) of rats regulates… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
1994
Highly Cited
1994
BACKGROUND To determine whether elevations of plasma norepinephrine (NE) in major depression represent increased sympathetic… Expand
Is this relevant?
Highly Cited
1993
Highly Cited
1993
OBJECTIVE To determine whether clomipramine hydrochloride, a serotonin reuptake blocker with unique anti-obsessional properties… Expand
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Prompted by a recent study suggesting that the combination of desipramine hydrochloride and fluoxetine down-regulates beta… Expand
Is this relevant?
Highly Cited
1990
Highly Cited
1990
To evaluate whether serotonin reuptake inhibition is critical to the treatment of obsessive-compulsive disorder, 40 outpatients… Expand
Is this relevant?
1990
1990
Twenty-three women with nonpurging bulimia underwent a 12-week, double-blind, placebo-controlled trial of desipramine… Expand
Is this relevant?
Highly Cited
1989
Highly Cited
1989
We conducted a double-blind, random assignment, six-week comparison of desipramine hydrochloride (n = 24), lithium carbonate (n… Expand
Is this relevant?
Highly Cited
1989
Highly Cited
1989
Forty-eight children and adolescents with severe primary obsessive-compulsive disorder completed a 10-week double-blind crossover… Expand
Is this relevant?
Highly Cited
1984
Highly Cited
1984
We conducted an open clinical trial of desipramine hydrochloride or lithium carbonate as adjuncts to psychotherapy in cocaine… Expand
Is this relevant?