Desipramine Hydrochloride

Known as: Desipramine Hydrochloride [Chemical/Ingredient], Hydrochloride, Desipramine, desipramine hcl 
The hydrochloride salt form of desipramine, a secondary amine tricyclic antidepressant (TCA). In the central nervous system (CNS), desipramine… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2016
0246819652016

Papers overview

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Highly Cited
2005
Highly Cited
2005
BACKGROUND There is substantial evidence that antidepressant medications treat moderate to severe depression effectively, but… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The etiology of depressive illness has been linked with brain monoaminergic neuronal dysfunction, yet the development… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND To determine whether elevations of plasma norepinephrine (NE) in major depression represent increased sympathetic… (More)
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Highly Cited
1993
Highly Cited
1993
OBJECTIVE To determine whether clomipramine hydrochloride, a serotonin reuptake blocker with unique anti-obsessional properties… (More)
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Highly Cited
1991
Highly Cited
1991
Prompted by a recent study suggesting that the combination of desipramine hydrochloride and fluoxetine down-regulates beta… (More)
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1991
1991
Twenty-six children and adolescents with severe primary obsessive-compulsive disorder receiving long-term clomipramine… (More)
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Highly Cited
1990
Highly Cited
1990
To evaluate whether serotonin reuptake inhibition is critical to the treatment of obsessive-compulsive disorder, 40 outpatients… (More)
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1990
1990
Tricyclic antidepressants cause orthostatic hypotension and have antiarrhythmic effects that may be partially due to effects on… (More)
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Highly Cited
1989
Highly Cited
1989
Forty-eight children and adolescents with severe primary obsessive-compulsive disorder completed a 10-week double-blind crossover… (More)
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Highly Cited
1989
Highly Cited
1989
We conducted a double-blind, random assignment, six-week comparison of desipramine hydrochloride (n = 24), lithium carbonate (n… (More)
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