Desipramine

Known as: DMI, 3-(10,11-DIHYDRO-5H-dibenzo[b,F]azepin-5-yl)-N-methylpropan-1-amine, Desipraminum 
An active metabolite of imipramine, a tertiary amine and a synthetic tricyclic derivative of the antidepressant. Desipramine enhances monoamine… (More)

Topic mentions per year

Topic mentions per year

1961-2017
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Papers overview

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Highly Cited
2011
Highly Cited
2011
Arbuscular mycorrhiza (AM) is a root endosymbiosis between plants and glomeromycete fungi. It is the most widespread terrestrial… (More)
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Highly Cited
2007
Highly Cited
2007
Tricyclic antidepressants exert their pharmacological effect-inhibiting the reuptake of serotonin, norepinephrine, and dopamine… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND & AIMS Studies of antidepressants and psychological treatments in functional bowel disorders (FBD) are… (More)
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Highly Cited
1999
Highly Cited
1999
Rationale: The forced swimming test (FST) is a behavioral test in rodents that predicts the clinical efficacy of many types of… (More)
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Highly Cited
1998
Highly Cited
1998
Studies using behavioral methods, such as head-turning experiments, in which children are conditioned to turn their heads toward… (More)
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Highly Cited
1995
Highly Cited
1995
The influence of chronic electroconvulsive seizure (ECS) or antidepressant drug treatments on expression of brain-derived… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND To determine whether elevations of plasma norepinephrine (NE) in major depression represent increased sympathetic… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND Amitriptyline reduces the pain caused by peripheral-nerve disease, but treatment is often limited by side effects… (More)
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Highly Cited
1987
Highly Cited
1987
Rats exposed chronically (5–9 weeks) to a variety of mild unpredictable stressors showed a reduced consumption of and preference… (More)
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Highly Cited
1985
Highly Cited
1985
A novel test procedure for antidepressants was designed in which a mouse is suspended by the tail from a lever, the movements of… (More)
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