Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Aminacrine

Known as: Aminoacrine, 9-Acridinamine, 9 Aminoacridine 
A highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It… Expand
National Institutes of Health

Related topics

Related topics

28 relations

Narrower (16)

1-nitro-9-aminoacridine4'-(9-acridinylamino)methanesulfonanilide9-AMA9-amino-10-methylacridinium
Expand

Broader (7)

AcridinesAminoacridinesAnti-Bacterial AgentsAnti-Infective Agents, Local
Expand
Aminacrine Hydrochlorideanalogs & derivativesaspects of radiation effectschemical synthesis
Expand

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2001
Review
2001
Acridine-a neglected antibacterial chromophore.
  • M. Wainwright
  • The Journal of antimicrobial chemotherapy
  • 2001
    • Corpus ID: 21649701
The use of acridines as antimicrobial agents was first proposed by Ehrlich and Benda in 1912, and the first clinical use of these… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The ability of the Comet assay to discriminate between genotoxins and cytotoxins.
The Comet assay has been used widely in genetic toxicology, radiation biology and medical and environmental research. This assay… Expand
  • table I
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Antagonism of immunostimulatory CpG-oligodeoxynucleotides by quinacrine, chloroquine, and structurally related compounds.
Phosphorothioate oligodeoxynucleotides containing CpG (CpG-ODN) activate immune responses. We report that quinacrine, chloroquine… Expand
  • figure 3
  • figure 1
  • figure 2
  • figure 6
  • figure 4
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Cholinesterase Inhibitors in Alzheimer's Disease
  • K. Davis
  • Neuropsychopharmacology
  • 1994
    • Corpus ID: 5977401
Data generated to date by a number of large studies (Eagger et al, Davis et al, Farlow et al, and Murphy et al) indicate that… Expand
Is this relevant?
Review
1993
Review
1993
Brain selective inhibition of acetylcholinesterase: a novel approach to therapy for Alzheimer's disease.
It could be argued that clinical experience with cholinergic drugs in the therapy of AD has not yet shown relevant symptomatic… Expand
Is this relevant?
Highly Cited
1987
Highly Cited
1987
SOS-inducing activity of chemical carcinogens and mutagens in Salmonella typhimurium TA1535/pSK1002: examination with 151 chemicals.
The umu test system is a newly developed method to evaluate genotoxic activities of a wide variety of environmental carcinogens… Expand
Is this relevant?
Highly Cited
1984
Highly Cited
1984
Quenching of DNA-ethidium fluorescence by amsacrine and other antitumor agents: a possible electron-transfer effect.
The antitumor agent amsacrine, 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA), when bound to double-stranded DNA… Expand
Is this relevant?
Highly Cited
1983
Highly Cited
1983
Revised methods for the Salmonella mutagenicity test.
The methods for detecting carcinogens and mutagens with the Salmonella mutagenicity test were described previously (Ames et al… Expand
  • table 2
  • table 4
  • figure 2
Is this relevant?
Highly Cited
1978
Highly Cited
1978
Testing of known carcinogens and noncarcinogens for their ability to induce unscheduled DNA synthesis in HeLa cells.
The ability of 51 compounds, of known carcinogenic potential, to induce "unscheduled DNA synthesis" in HeLa cells has been tested… Expand
  • table 1
Is this relevant?
Highly Cited
1968
Highly Cited
1968
The interaction of aminoacridines with nucleic acids
 
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE