Aminacrine

Known as: Aminoacrine, 9-Acridinamine, 9 Aminoacridine 
A highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It… (More)
National Institutes of Health

Related topics

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28 relations

Narrower (16)

1-nitro-9-aminoacridine4'-(9-acridinylamino)methanesulfonanilide9-AMA9-amino-10-methylacridinium
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Broader (7)

AcridinesAminoacridinesAnti-Bacterial AgentsAnti-Infective Agents, Local
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Aminacrine Hydrochlorideanalogs & derivativesaspects of radiation effectschemical synthesis
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Papers overview

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2012
2012
Sublimation of new matrix candidates for high spatial resolution imaging mass spectrometry of lipids: enhanced information in both positive and negative polarities after 1,5-diaminonapthalene…
Matrix sublimation has demonstrated to be a powerful approach for high-resolution matrix-assisted laser desorption ionization… (More)
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Highly Cited
2008
Highly Cited
2008
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of cellular glycerophospholipids enabled by multiplexed solvent dependent analyte-matrix interactions.
A matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) based approach was developed for… (More)
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Highly Cited
1999
Highly Cited
1999
Subtype-dependence of NMDA receptor channel open probability.
NMDA receptor-mediated calcium transients play a critical role in synaptogenesis, synaptic plasticity, and excitotoxicity. NMDA… (More)
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Highly Cited
1998
Highly Cited
1998
Antagonism of immunostimulatory CpG-oligodeoxynucleotides by quinacrine, chloroquine, and structurally related compounds.
Phosphorothioate oligodeoxynucleotides containing CpG (CpG-ODN) activate immune responses. We report that quinacrine, chloroquine… (More)
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Highly Cited
1998
Highly Cited
1998
The ability of the Comet assay to discriminate between genotoxins and cytotoxins.
The Comet assay has been used widely in genetic toxicology, radiation biology and medical and environmental research. This assay… (More)
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Highly Cited
1993
Highly Cited
1993
Inhibitors of human immunodeficiency virus integrase.
In an effort to further extend the number of targets for development of antiretroviral agents, we have used an in vitro integrase… (More)
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1984
1984
Quenching of DNA-ethidium fluorescence by amsacrine and other antitumor agents: a possible electron-transfer effect.
The antitumor agent amsacrine, 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA), when bound to double-stranded DNA… (More)
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Highly Cited
1983
Highly Cited
1983
Revised methods for the Salmonella mutagenicity test.
The methods for detecting carcinogens and mutagens with the Salmonella mutagenicity test were described previously (Ames et al… (More)
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1983
1983
Optical measurements of ΔpH and Δψ in corn root membrne vesicles: Kinetic analysis of Cl− effects on a proton-translocating ATPase
The optical probes 9-aminoacridine, quinacrine, and bis (3-propyl-5-oxoisoxazol-4-yl) pentamethine oxonol (OX-VI) were used to… (More)
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1975
1975
Relative thermostability of the chloroplast envelope
Intact isolated chloroplasts from leaves of Spinacia oleracea L. were subjected to heat treatment. After heating, the integrity… (More)
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