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2-hydroxydesipramine

Known as: 2-OH-DMI, 2-hydroxy-desipramine, 2-hydroxydesmethylimipramine 
 
National Institutes of Health

Papers overview

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2009
2009
ObjectiveThe clinical relevance of the CYP2D6 oxidation polymorphism in the treatment of depression with desipramine (DMI) was… Expand
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2009
2009
The potential for cytochrome P450 (CYP) 2D6 substrates to interact with desvenlafaxine (administered as desvenlafaxine succinate… Expand
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2002
2002
Terbinafine-CYP2D6 inhibition was evaluated by assessing 48-hour concentration-time profiles of the tricyclic antidepressant… Expand
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1997
1997
The antidepressant desipramine (DMI) and its principal metabolite 2-hydroxydesipramine (HDMI) have been radiolabeled with 11C for… Expand
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1993
1993
OBJECTIVE To assess the developmental effects of desipramine (DMI) treatment on the electrocardiogram (ECG), we investigated… Expand
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1993
1993
The pharmacokinetic interactions between the selective serotonin reuptake inhibitor citalopram, given as an oral dose of 40 mg… Expand
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1986
1986
Desipramine and its metabolite 2-hydroxydesipramine were measured in the milk of a nursing mother and in the plasma of the mother… Expand
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1985
1985
Studies of the relationship between plasma concentrations of desipramine hydrochloride and clinical response have shown… Expand
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1984
1984
Plasma levels of desipramine (DMI) and the unconjugated form of its principal metabolite 2-hydroxydesipramine (OH-D) were… Expand
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1979
1979
Abstract The tricyclic antidepressant imipramine and its metabolites desipramine, 2-hydroxyimipramine and 2-hydroxydesipramine… Expand
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