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Dynamic mapping of human cortical development during childhood through early adulthood.
We report the dynamic anatomical sequence of human cortical gray matter development between the age of 4-21 years using quantitative four-dimensional maps and time-lapse sequences. Thirteen healthyExpand
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Brain development during childhood and adolescence: a longitudinal MRI study
Pediatric neuroimaging studies, up to now exclusively cross sectional, identify linear decreases in cortical gray matter and increases in white matter across ages 4 to 20. In this large-scaleExpand
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Neurodevelopmental Trajectories of the Human Cerebral Cortex
Understanding the organization of the cerebral cortex remains a central focus of neuroscience. Cortical maps have relied almost exclusively on the examination of postmortem tissue to constructExpand
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Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder.
CONTEXT Various anatomic brain abnormalities have been reported for attention-deficit/hyperactivity disorder (ADHD), with varying methods, small samples, cross-sectional designs, and withoutExpand
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Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation
There is controversy over the nature of the disturbance in brain development that underpins attention-deficit/hyperactivity disorder (ADHD). In particular, it is unclear whether the disorder resultsExpand
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A Developmental Functional MRI Study of Prefrontal Activation during Performance of a Go-No-Go Task
This study examines important developmental differences in patterns of activation in the prefrontal cortex during performance of a Go-No-Go paradigm using functional magnetic resonance imagingExpand
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Quantitative brain magnetic resonance imaging in attention-deficit hyperactivity disorder.
BACKGROUND Anatomic magnetic resonance imaging (MRI) studies of attention-deficit hyperactivity disorder (ADHD) have been limited by small samples or measurement of single brain regions. Since theExpand
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Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia
Schizophrenia is a devastating neurodevelopmental disorder whose genetic influences remain elusive. We hypothesize that individually rare structural variants contribute to the illness. MicrodeletionsExpand
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Obsessive compulsive disorder in adolescence: an epidemiological study.
In the second part of a two-stage epidemiologic study of obsessive-compulsive symptoms in nonreferred adolescents, clinicians interviewed high school students selected from screening measuresExpand
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Quantitative MRI of the temporal lobe, amygdala, and hippocampus in normal human development: Ages 4–18 years
The volume of the temporal lobe, superior temporal gyrus, amygdala, and hippocampus was quantified from magnetic images of the brains of 99 healthy children and adolescents aged 4–18 years.Expand
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