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Cytochrome P450 2D6, human

Known as: Cytochrome P450, Subfamily IID, Xenobiotic Monooxygenase, P450-DB1 
Cytochrome P450 2D6 (497 aa, ~56 kDa) is encoded by the human CYP2D6 gene. This protein plays a role in flavoprotein metabolism.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Part I of this article discussed the potential functional importance of genetic mutations and alleles of the human cytochrome… Expand
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2004
2004
SummaryThe sparteine/debrisoquine oxidation polymorphism results from differences in the activity of one isozyme of cytochrome… Expand
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1995
1995
The highly specific mechanism of action of the selective serotonin re-uptake inhibitors (SSRIs) confers advantages on this group… Expand
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1995
1995
 
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1994
1994
The selectivity of carbon monoxide binding to specific human cytochrome P450 isozymes was investigated by studying its inhibition… Expand
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1994
1994
Following the characterization of theonellapeptolides Ia-Ie (2-6), another new tridecapeptide lactone named theonellapeptolide… Expand
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Review
1992
Review
1992
Host-specific factors influence risk for lung cancer. A few case-control and family studies of lung cancer susceptibility allowed… Expand
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Highly Cited
1989
Highly Cited
1989
Type 1, liver kidney microsomal autoantibodies (LKM-1) are associated with a subgroup of idiopathic autoimmune type, chronic… Expand
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1987
1987
Debrisoquine 4-hydroxylase (P450db1) was purified from rat liver microsomes. Polyclonal antibody was produced and, in conjunction… Expand
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1987
1987
In human liver microsomal preparations the neurotoxic chemical N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and several of… Expand
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