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Amitriptyline

Known as: 5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,D)cycloheptene, Amitriptylinum, Amitriptyline [Chemical/Ingredient] 
A derivative of dibenzocycloheptadiene and a tricyclic antidepressant. Amitriptyline inhibits the re-uptake of norepinephrine and serotonin by the… 
National Institutes of Health

Related topics

Related topics

41 relations

Narrower (9)

1-chloroamitriptylineAMITRIPTYLINE OXIDEAmitripAmitriptylin-neuraxpharm

Broader (7)

Adrenergic Uptake InhibitorsAminesAntidepressive AgentsDibenzocycloheptenes
Affective Disorders, PsychoticAmitriptyline / PerphenazineAmitriptyline HydrochlorideAmitriptyline Hydrochloride 50 MG Oral Tablet

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1992
Highly Cited
1992
Dextromethorphan and Mephenytoin Phenotyping of Patients Treated with Thioridazine or Amitriptyline
The metabolism of most tricyclic antidepressants and some phenothiazine neuroleptics is under the genetic control of hepatic… 
1984
1984
Evaluation of possible interactions between ethanol and trazodone or amitriptyline.
The pharmacodynamic effects of single doses of trazodone (100 mg), amitriptyline (50 mg) or placebo either alone or with ethanol… 
Review
1982
Review
1982
Amitriptyline overdose: clinical effects on tricyclic antidepressant plasma levels.
Tricyclic antidepressant (TCA) plasma levels after amitriptyline overdose were reviewed in a retrospective study. Amount of drug… 
1976
1976
A sensitive method for the determination of amitriptyline and nortriptyline in human plasma.
A highly sensitive and reproducible GLC technique for the quantitation of amitriptyline and nortriptyline is described. The lower… 
1974
1974
GLC method for quantitative determination of amitriptyline in human plasma.
Abstract: A GLC method was developed for the measurement of steady-state levels of amitriptyline and nortriptyline in human… 
Highly Cited
1973
Highly Cited
1973
CLINICAL RESPONSE TO AMITRIPTYLINE AMONG DEPRESSED WOMEN
Eighty-five female depressed patients were treated for 4 weeks with amitriptyline in a flexible dose (median, 150 mg daily… 
1973
1973
Pulmonary disease after amitriptyline overdosage.
of amitriptyline is reported.The disease process was accompanied by noticeable loss of lung compliance, and a gross diffusion… 
1972
1972
PREDICTORS OF AMITRIPTYLINE RESPONSE IN OUTPATIENT DEPRESSIVES
A step-search multiple regression procedure was applied to data obtained from 120 amitriptyline-treated and 138 placebo-treated… 
1971
1971
Chemistry and pharmacology of 5-methylene-4-substituted dibenzo(a,d)cycloheptenes.
Highly Cited
1967
Highly Cited
1967
Clinical effects and treatment of imipramine and amitriptyline poisoning in children.
Imipramine and amitriptyline are tricyclic antidepressant compounds whose chemical structure, dosage, pharmacology, and toxicity… 
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