Amitriptyline

Known as: 5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,D)cycloheptene, Amitriptylinum, Amitriptyline [Chemical/Ingredient] 
A derivative of dibenzocycloheptadiene and a tricyclic antidepressant. Amitriptyline inhibits the re-uptake of norepinephrine and serotonin by the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Relatively few selective substrate and inhibitor probes have been identified for human UDP-glucuronosyltransferases (UGTs). This… (More)
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Highly Cited
2006
Highly Cited
2006
The present study was performed to evaluate the effects of the tricyclic antidepressant amitriptyline on morphine tolerance in… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND AND AIMS Irritable bowel syndrome (IBS) is a disorder of intestinal hypersensitivity and altered motility, exacerbated… (More)
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Highly Cited
1999
Highly Cited
1999
A single injection of streptozocin (50 mg/kg, i.p.) led to the development of static and dynamic allodynia in the rat. The two… (More)
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Highly Cited
1996
Highly Cited
1996
OBJECTIVE This study was done to compare the effects of 6-week treatment with amitriptyline on hypothalamic-pituitary… (More)
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Highly Cited
1995
Highly Cited
1995
OBJECTIVE To determine whether, in the treatment of major depression in primary care, a brief psychological treatment (problem… (More)
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Highly Cited
1994
Highly Cited
1994
OBJECTIVE To compare the relative efficacy and tolerability of amitriptyline, cyclobenzaprine, and placebo in the treatment of… (More)
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Highly Cited
1988
Highly Cited
1988
In a double-blind, randomized, crossover study, 58 patients with postherpetic neuralgia received 6-week courses of amitriptyline… (More)
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Highly Cited
1987
Highly Cited
1987
In a randomized, double-blind crossover study, 29 patients with painful diabetic neuropathy received 6 weeks of amitriptyline and… (More)
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Highly Cited
1986
Highly Cited
1986
Sixty-two patients with fibromyalgia were randomly assigned to receive 25 mg of amitriptyline at night, 500 mg of naproxen twice… (More)
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