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This article provides a status report on the global burden of cancer worldwide using the GLOBOCAN 2018 estimates of cancer… Expand Cancer constitutes an enormous burden on society in more and less economically developed countries alike. The occurrence of… Expand Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the… Expand BACKGROUND
Bevacizumab, a monoclonal antibody against vascular endothelial growth factor, has shown promising preclinical and… Expand Inactivation of the genes involved in DNA mismatch repair is associated with microsatellite instability (MSI) in colorectal… Expand The authors are grateful to the members of their laboratories for their contributions to the reviewed studies and for their… Expand PURPOSE
We developed and validated a brief, yet sensitive, 33-item general cancer quality-of-life (QL) measure for evaluating… Expand Mutations of the p53 gene occur commonly in colorectal carcinomas and the wild-type p53 allele is often concomitantly deleted… Expand WE have hypothesized that end-to-end chromosome fusions observed in some tumours could play a part in genetic instability… Expand Previous studies have demonstrated that allelic deletions of the short arm of chromosome 17 occur in over 75% of colorectal… Expand