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APC gene

Known as: Genes, APC, DP2, adenomatous polyposis coli 
Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial… 
National Institutes of Health

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APC Gene Mut Anal Bld/TAPC protein, humanAdenocarcinoma of rectumAdenocarcinoma of the large intestine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
A genome screen of families at high risk for Hodgkin lymphoma: evidence for a susceptibility gene on chromosome 4
Hodgkin’s disease was recently designated Hodgkin lymphoma (HL) in the World Health Organization Classification.1 The National… 
2004
2004
Chemotherapy resistant ovarian cancer in carriers of an hMSH2 mutation?
Hereditary Non-Polyposis Colorectal Cancer (HNPCC, Lynch syndrome) is an autosomal dominant condition of cancer susceptibility… 
Review
1994
Review
1994
Silent Adrenal Nodules in von Hippel-Lindau Disease Suggest Pheochromocytoma
Von Hippel-Lindau disease is an autosomal-dominant disorder characterized by retinal angiomatosis, cerebellar hemangioblastoma… 
Highly Cited
1993
Highly Cited
1993
Loss of heterozygosity in familial breast carcinomas.
Three loci have been implicated in the etiology of familial breast cancer; the BRCA1 locus on 17q, the p53 gene on 17p, and the… 
1991
1991
Value of combined phenotypic markers in identifying inheritance of familial adenomatous polyposis.
Familial adenomatous polyposis is an autosomal dominant disease characterised by the development of hundreds of colorectal… 
1987
1987
Binding of monoclonal antibody (4F2) to its cell surface antigen on dispersed adenomatous parathyroid cells raises cytosolic calcium and inhibits parathyroid hormone secretion.
In the course of characterizing monoclonal antibodies (MAbs) recognizing cell surface antigens on dispersed human parathyroid… 
1986
1986
Analyses of prealbumin mRNAs in individuals with familial amyloidotic polyneuropathy.
The distribution of prealbumin mRNA in various tissues of a control subject and an individual with familial amyloidotic… 
Highly Cited
1982
Highly Cited
1982
A familial hemorrhagic diathesis in a Dutch family: an inherited deficiency of alpha 2-antiplasmin.
This study concerns a case of congenital homozygous deficiency in alpha 2-antiplasmin associated with a severe hemorrhagic… 
1978
1978
Plasma hormone profiles of young women at risk for familial breast cancer.
The plasma hormone concentrations of 30 young women, who were judged by genetic analysis to be at high risk for familial breast… 
1965
1965
FAMILIAL SUPRAVALVAR AORTIC STENOSIS
Though supravalvar aortic stenosis is uncommon and fewer than 80 cases have been described, nevertheless, a clinical picture is… 
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