Adenocarcinoma of the large intestine

Known as: Adenocarcinoma of Large Intestine, Large Bowel Adenocarcinoma, Colorectal Adenocarcinoma 
The most common type of colorectal carcinoma. It is characterized by the presence of malignant glandular epithelial cells invading through the… (More)
National Institutes of Health

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APC geneBRAF geneCSMD1 geneColorectal Region
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Broader (1)

Colorectal Carcinoma

Papers overview

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Highly Cited
2010
Highly Cited
2010
Toward curative treatment of peritoneal carcinomatosis from nonovarian origin by cytoreductive surgery combined with perioperative intraperitoneal chemotherapy: a multi-institutional study of 1,290…
BACKGROUND Peritoneal carcinomatosis (PC) from nonovarian malignancies long has been regarded as a terminal disease. Over the… (More)
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Highly Cited
2009
Highly Cited
2009
Complete cytoreductive surgery plus intraperitoneal chemohyperthermia with oxaliplatin for peritoneal carcinomatosis of colorectal origin.
PURPOSE To compare the long-term survival of patients with isolated and resectable peritoneal carcinomatosis (PC) in comparable… (More)
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Highly Cited
2008
Highly Cited
2008
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.
Tumors contain oxygenated and hypoxic regions, so the tumor cell population is heterogeneous. Hypoxic tumor cells primarily use… (More)
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Highly Cited
2005
Highly Cited
2005
Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer).
BACKGROUND Germ-line mutations in the mismatch-repair genes MLH1, MSH2, MSH6, and PMS2 lead to the development of the Lynch… (More)
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Highly Cited
2004
Highly Cited
2004
Severe hepatic sinusoidal obstruction associated with oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.
BACKGROUND In advanced metastatic colorectal adenocarcinoma, the addition of a neo-adjuvant systemic treatment to surgery might… (More)
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Highly Cited
2003
Highly Cited
2003
Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2.
Angiogenesis plays a critical role in metastasis and tumor growth. Human tumors, including colorectal adenocarcinoma, secrete… (More)
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Highly Cited
1999
Highly Cited
1999
CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression.
The molecular basis of aberrant hypermethylation of CpG islands observed in a subset of human colorectal tumors is unknown. One… (More)
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Highly Cited
1997
Highly Cited
1997
The prognostic significance of intratumoral natural killer cells in patients with colorectal carcinoma.
BACKGROUND Natural killer (NK) cells have a spontaneous cytotoxic capacity-against tumor cells. These cells represent a small… (More)
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Highly Cited
1997
Highly Cited
1997
Prognostic value of tumour-infiltrating lymphocytes (TILs) in colorectal cancer.
Clinical follow-up data of 276 colorectal adenocarcinoma patients treated in Kuopio University Hospital between 1976 and 1986 and… (More)
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Highly Cited
1976
Highly Cited
1976
Classification of human colorectal adenocarcinoma cell lines.
Eleven human colorectal adenocarcinoma cell lines established in this laboratory were classified into three groups based on… (More)
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