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BRAF gene

Known as: RAFB1, B-Raf Proto-Oncogene, Serine/Threonine Kinase Gene, B-Raf proto-oncogene, serine/threonine kinase 
A gene that makes a protein called B-RAF, which is involved in sending signals in cells and in cell growth. This gene may be mutated (changed) in… 
National Institutes of Health

Related topics

Related topics

48 relations
Adenocarcinoma of rectumAdenocarcinoma of the large intestineAngiogenic ProcessBRAF NM_004333.4:c.1405_1407delGGAinsAGC

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Molecular genetic changes in benign colorectal tumors synchronous with microsatellite unstable carcinomas do not support a field defect.
BACKGROUND A colorectal cancer may develop through a particular molecular genetic pathway, raising the question of whether the… 
2016
2016
P2A-Fluorophore Tagging of BRAF Tightly Links Expression to Fluorescence In Vivo
The Braf proto-oncogene is a key component of the mitogen-activated protein kinase signaling cascade and is a critical regulator… 
2015
2015
IRS 2 Copy Number Gain , KRAS and BRAF Mutation Status as Predictive Biomarkers for Response to the IGF-1 R / IR Inhibitor BMS-754807 in Colorectal Cancer Cell Lines
Insulin-like growth factor receptor 1 (IGF-1R)–targeting therapies are currently at an important crossroad given the low clinical… 
2015
2015
A2.31 Braf (v raf murine sarcoma viral oncogene homologue B1) mutations in rheumatoid arthritis patients
Background Rheumatoid arthritis (RA) is a chronic autoimmune disease characterised by excessive immune responses resulting in… 
2014
2014
Cell Cycle and Senescence Activating BRAF and PIK 3 CA Mutations Cooperate to Promote Anaplastic Thyroid Carcinogenesis
Thyroid malignancies are the most common type of endocrine tumors. Of the various histologic subtypes, anaplastic thyroid… 
2012
2012
A Micro-RNA Connection in BRaf V600E-Mediated Premature Senescence of Human Melanocytes
Recent high-throughput-sequencing of the cancer genome has identified oncogenic mutations in BRaf genetic locus as one of the… 
2009
2009
EGFR gene copy number, KRAS and BRAF status, PTEN and AKT expression analysis in patients with metastatic colon cancer treated with anti-EGFR monoclonal antibodies ± chemotherapy.
e15055 Background: Cetuximab and panitumumab have proven to be effective in metastatic colon cancer (mCRC). KRAS mutation has… 
2006
2006
Matrix Remodeling that Predict a Preferential Role of BRAF in Extracellular Thyroid Cells Is Associated with Gene Expression Profiles Conditional Activation of RET / PTC 3 and BRAFV 600 E in Updated
Papillary thyroid cancers (PTC) are associated with nonoverlapping mutations of genes coding for mitogen-activated protein kinase… 
2004
2004
Fiche no51 : B-Raf (BRAF1, RAFB1, Rmil).
2004
2004
[Chart #51: B-Raf (BRAF1, RAFB1, Rmil].
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