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BRAF gene

Known as: RAFB1, B-Raf Proto-Oncogene, Serine/Threonine Kinase Gene, B-Raf proto-oncogene, serine/threonine kinase 
A gene that makes a protein called B-RAF, which is involved in sending signals in cells and in cell growth. This gene may be mutated (changed) in… 
National Institutes of Health

Related topics

Related topics

48 relations
Adenocarcinoma of rectumAdenocarcinoma of the large intestineAngiogenic ProcessBRAF NM_004333.4:c.1405_1407delGGAinsAGC

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
KRAS and BRAF somatic mutations in colonic polyps and the risk of metachronous neoplasia
Background & aims High-risk features of colonic polyps are based on size, number, and pathologic characteristics. Surveillance… 
2017
2017
Molecular genetic changes in benign colorectal tumors synchronous with microsatellite unstable carcinomas do not support a field defect.
BACKGROUND A colorectal cancer may develop through a particular molecular genetic pathway, raising the question of whether the… 
2016
2016
BRAF Mutation Is Associated with Improved Local Control of Melanoma Brain Metastases Treated with Gamma Knife Radiosurgery
Objectives Evidence has implicated a possible role of tumor mutation status on local control (LC) with radiotherapy. BRAF is a… 
2015
2015
High-Resolution Melting Is a Sensitive, Cost-Effective, Time-Saving Technique for BRAF V600E Detection in Thyroid FNAB Washing Liquid: A Prospective Cohort Study
Objective: The diagnostic accuracy of thyroid fine needle aspiration biopsy (FNAB) can be improved by the combination of… 
2015
2015
IRS 2 Copy Number Gain , KRAS and BRAF Mutation Status as Predictive Biomarkers for Response to the IGF-1 R / IR Inhibitor BMS-754807 in Colorectal Cancer Cell Lines
Insulin-like growth factor receptor 1 (IGF-1R)–targeting therapies are currently at an important crossroad given the low clinical… 
Highly Cited
2014
Highly Cited
2014
Activating BRAF and PIK3CA Mutations Cooperate to Promote Anaplastic Thyroid Carcinogenesis
Thyroid malignancies are the most common type of endocrine tumors. Of the various histologic subtypes, anaplastic thyroid… 
2014
2014
IRS2 Copy Number Gain, KRAS and BRAF Mutation Status as Predictive Biomarkers for Response to the IGF-1R/IR Inhibitor BMS-754807 in Colorectal Cancer Cell Lines
Insulin-like growth factor receptor 1 (IGF-1R)–targeting therapies are currently at an important crossroad given the low clinical… 
2010
2010
Genetic Interaction Between NRAS and BRAF Mutations and PTEN / MMAC 1 Inactivation in Melanoma
Extant evidence implicates growth factor signaling in the pathogenesis of many tumor types, including cutaneous melanoma… 
2009
2009
BRAF and RKIP are significantly decreased in cutaneous squamous cell carcinoma
Background. Actinic keratosis (AK) is a well-established pre-cancerous skin lesion that has the potential to progress to squamous… 
2006
2006
Altered Gene Expression Pattern in Peripheral Blood Leukocytes from Patients with Arterial Hypertension
Abstract:  The role of various inflammatory mechanisms and oxidative stress in the development of atherosclerosis and arterial… 
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