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BRAF gene

Known as: RAFB1, B-Raf Proto-Oncogene, Serine/Threonine Kinase Gene, B-Raf proto-oncogene, serine/threonine kinase 
A gene that makes a protein called B-RAF, which is involved in sending signals in cells and in cell growth. This gene may be mutated (changed) in… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Erdheim-Chester Disease (ECD) is a rare, potentially fatal, multi-organ myeloid neoplasm occurring mainly in adults. The… Expand
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Highly Cited
2015
Highly Cited
2015
Mutations in genes such as KRAS, NRAS, BRAF and PIK3CA have become an important part of colorectal carcinoma evaluation. The aim… Expand
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Highly Cited
2014
Highly Cited
2014
Thyroid malignancies are the most common type of endocrine tumors. Of the various histologic subtypes, anaplastic thyroid… Expand
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2014
2014
Treatment of BRAF mutant melanomas with specific BRAF inhibitors leads to tumor remission. However, most patients eventually… Expand
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2013
2013
BackgroundActivating KRAS and BRAF mutations predict unresponsiveness to EGFR-targeting therapies in colorectal cancer (CRC), but… Expand
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2013
2013
BackgroundPrevalence and distribution of pathogenetic mutations in BRAF and NRAS genes were evaluated in multiple melanoma… Expand
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2010
2010
Extant evidence implicates growth factor signaling in the pathogenesis of many tumor types, including cutaneous melanoma… Expand
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2009
2009
Background. Actinic keratosis (AK) is a well-established pre-cancerous skin lesion that has the potential to progress to squamous… Expand
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2006
2006
The role of various inflammatory mechanisms and oxidative stress in the development of atherosclerosis and arterial hypertension… Expand
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Highly Cited
2004
Highly Cited
2004
Extant evidence implicates growth factor signaling in the pathogenesis of many tumor types, including cutaneous melanoma… Expand
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