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Adenomatous Polyposis Coli

Known as: Colus, Polyposis, Adenomatous Polyposis Colus, Familial Polyposis Syndrome 
An autosomal dominant disorder, characterized by the presence of multiple adenomas in the colon and rectum. It is caused by a germline mutation in… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Aberrant Wnt/β-catenin signaling has often been reported in different cancers, particularly colorectal cancer (CRC), and this… Expand
Review
2019
Review
2019
Treatment of young adults with colorectal cancer (CRC) represents an unmet clinical need, especially as diagnosis in this… Expand
Review
2019
Review
2019
Colorectal cancer (CRC) is a leading cause of death among digestive diseases and the second leading cause of cancer-related death… Expand
Review
2018
Review
2018
The canonical Wnt/β-catenin signaling pathway, an important modulator of progenitor cell proliferation and differentiation, is… Expand
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Review
2018
Review
2018
Colorectal cancer (CRC) is one of the major health threats in developed countries. Changes in dietary components, such as more… Expand
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Review
2018
Review
2018
Background: Familial hypercholesterolemia (FH) and other extreme elevations in low-density lipoprotein cholesterol significantly… Expand
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Review
2017
Review
2017
PURPOSE The true benefit of autologous platelet concentrates (APCs) for enhancing the healing of postextraction sites is still a… Expand
Highly Cited
1995
Highly Cited
1995
The APC tumor-suppressor protein associates with beta-catenin, a cell adhesion protein that is upregulated by the WNT1 oncogene… Expand
Highly Cited
1991
Highly Cited
1991
DNA from 61 unrelated patients with adenomatous polyposis coli (APC) was examined for mutations in three genes (DP1, SRP19, and… Expand
Highly Cited
1988
Highly Cited
1988
Because most colorectal carcinomas appear to arise from adenomas, studies of different stages of colorectal neoplasia may shed… Expand