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Adenomatous Polyposis Coli

Known as: Colus, Polyposis, Adenomatous Polyposis Colus, Familial Polyposis Syndrome 
An autosomal dominant disorder, characterized by the presence of multiple adenomas in the colon and rectum. It is caused by a germline mutation in… 
National Institutes of Health

Related topics

Related topics

48 relations
APC geneAPC protein, humanAPCDD1 geneAbdominal Pain

Narrower (3)

Colorectal Adenomatous Polyposis, Autosomal RecessiveFAMILIAL ADENOMATOUS POLYPOSIS, ATTENUATED (disorder)POLYPOSIS SYNDROME, HEREDITARY MIXED, 1

Broader (2)

Familial diseaseOther diagnosis for the colon

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Ionic liquids containing the tris(pentafluoroethyl)trifluorophosphate anion: a new class of highly selective and ultra hydrophobic solvents for the extraction of polycyclic aromatic hydrocarbons…
A new class of ionic liquids (ILs) containing the tris(pentafluoroethyl)trifluorophosphate (FAP) anion are paired with… 
Highly Cited
2006
Highly Cited
2006
Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis.
There is considerable debate whether peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) ligands potentiate or… 
Review
1999
Review
1999
Lymphoma of the gastrointestinal tract.
Non-Hodgkin's lymphoma (NHL) of the gastrointestinal (GI) tract accounts for 4% to 20% of all NHLs and is the most common… 
Highly Cited
1997
Highly Cited
1997
Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein.
Mutation of the adenomatous polyposis coli (APC) gene is an early step in the initiation of colon cancer. Because the… 
Highly Cited
1997
Highly Cited
1997
Familial intracranial aneurysms
Highly Cited
1996
Highly Cited
1996
Alteration of beta-catenin expression in colonic epithelial cells of familial adenomatous polyposis patients.
It has been found that beta-catenin, a key regulator of the cadherin-mediated cell adhesion system, forms complexes with… 
Highly Cited
1988
Highly Cited
1988
A protective effect of sulindac against chemically‐induced primary colonic tumours in mice
Sulindac, a non‐steroidal anti‐inflammatory drug, has been reported to lead to tumour regression in cases of human polyposis coli… 
Highly Cited
1988
Highly Cited
1988
Loss of constitutional heterozygosity in colon carcinoma from patients with familial polyposis coli
Recent studies have suggested a critical role of specific gene loss in several embryonic tumours1–6 and certain adult cancers7–12… 
Highly Cited
1986
Highly Cited
1986
A sensitive and practical assay for thyroid-stimulating antibodies using crude immunoglobulin fractions precipitated with polyethylene glycol.
A simple, sensitive, and practical assay for thyroid-stimulating autoantibodies (TSAb) was developed in which cryopreserved… 
Highly Cited
1974
Highly Cited
1974
Abnormal Antithrombin III (Antithrombin III ‘Budapest’) as a Cause of a Familial Thrombophilia
Summary A family with a high incidence of spontaneous thromboembolism has been investigated and those members affected were found… 
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