Adenomatous Polyposis Coli

Known as: Colus, Polyposis, Adenomatous Polyposis Colus, Familial Polyposis Syndrome 
An autosomal dominant disorder, characterized by the presence of multiple adenomas in the colon and rectum. It is caused by a germline mutation in… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1935-2018
0500100019352017

Papers overview

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Review
2016
Review
2016
Hemophagocytic lymphohistiocytosis (HLH) is a life threatening hyperinflammatory syndrome characterized by excessive activation… (More)
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Review
2016
Review
2016
Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disease in adults. Classical ALS is characterized by the… (More)
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Highly Cited
2003
Highly Cited
2003
Cell polarity is a fundamental property of all cells. In higher eukaryotes, the small GTPase Cdc42, acting through a Par6… (More)
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Highly Cited
2001
Highly Cited
2001
The adenomatous polyposis coli (APC) gene is a tumor suppressor gene associated with both familial and sporadic cancer. Despite… (More)
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Highly Cited
2000
Highly Cited
2000
Germ-line mutations in the tumor suppressor gene APC are associated with hereditary familial adenomatous polyposis (FAP), and… (More)
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Highly Cited
1999
Highly Cited
1999
Ectopic expression of certain Wnt genes in mouse mammary tissue is tumorigenic, and mutations that stabilize beta-catenin are… (More)
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Highly Cited
1998
Highly Cited
1998
Germ-line mutations of the tumor suppressor APC are implicated in attenuated adenomatous polyposis coli (AAPC), a variant of… (More)
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Highly Cited
1995
Highly Cited
1995
The APC tumor-suppressor protein associates with beta-catenin, a cell adhesion protein that is upregulated by the WNT1 oncogene… (More)
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Highly Cited
1994
Highly Cited
1994
Mutation of the adenomatous polyposis coli (APC) gene was analyzed in 500 colorectal tumors from 70 familial adenomatous… (More)
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Highly Cited
1991
Highly Cited
1991
DNA from 61 unrelated patients with adenomatous polyposis coli (APC) was examined for mutations in three genes (DP1, SRP19, and… (More)
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