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A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease…
This work estimated deaths and disability-adjusted life years (DALYs) attributable to the independent effects of 67 risk factors and clusters of risk factors for 21 regions in 1990 and 2010 and calculated the burden attributable to each risk factor exposure compared with the theoretical-minimum-risk exposure. Expand
Diabetes and Cancer: A Consensus Report
A consensus statement of experts assembled jointly by the American Diabetes Association and the American Cancer Society reviews the state of science concerning the association between diabetes and cancer incidence or prognosis and whether diabetes treatments influence the risk of cancer or cancer prognosis. Expand
Reproducibility and validity of an expanded self-administered semiquantitative food frequency questionnaire among male health professionals.
- E. Rimm, E. Giovannucci, M. Stampfer, G. Colditz, L. Litin, W. Willett
- American journal of epidemiology
- 15 May 1992
The authors assessed the reproducibility and validity of an expanded 131-item semiquantitative food frequency questionnaire used in a prospective study among 51,529 men and found that it provides a useful measure of intake for many nutrients over a one-year period. Expand
Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes.
- H. Bischoff-Ferrari, E. Giovannucci, W. Willett, T. Dietrich, B. Dawson-Hughes
- The American journal of clinical nutrition
- 1 July 2006
Evidence from studies that evaluated thresholds for serum 25(OH)D concentrations in relation to bone mineral density, lower-extremity function, dental health, and risk of falls, fractures, and colorectal cancer suggests that an increase in the currently recommended intake of vitamin D is warranted. Expand
Diet quality and major chronic disease risk in men and women: moving toward improved dietary guidance.
- M. McCullough, D. Feskanich, +7 authors W. Willett
- The American journal of clinical nutrition
- 1 December 2002
The AHEI predicted chronic disease risk better than did the RFS (or the HEI, in previous research) primarily because of a strong inverse association with CVD. Expand
Physical Activity, Obesity, and Risk for Colon Cancer and Adenoma in Men
- E. Giovannucci, A. Ascherio, E. Rimm, G. Colditz, M. Stampfer, W. Willett
- Annals of Internal Medicine
- 1 March 1995
The hypotheses that physical inactivity, obesity, and height increase the risk for colon cancer and adenoma independently of each other and of diet are addressed, and that the abdominal pattern of obesity is an additional independent risk factor are addressed. Expand
Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials.
- H. Bischoff-Ferrari, W. Willett, J. Wong, E. Giovannucci, T. Dietrich, B. Dawson-Hughes
- 11 May 2005
Oral vitamin D supplementation between 700 to 800IU/d appears to reduce the risk of hip and any nonvertebral fractures in ambulatory or institutionalized elderly persons and an oral vitamin D dose of 400 IU/d is not sufficient for fracture prevention. Expand
Prospective study of predictors of vitamin D status and cancer incidence and mortality in men.
- E. Giovannucci, Y. Liu, +4 authors W. Willett
- Journal of the National Cancer Institute
- 5 April 2006
Low levels of vitamin D may be associated with increased cancer incidence and mortality in men, particularly for digestive-system cancers, when controlled further for body mass index or physical activity level. Expand
CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer
CIMP-high appears to be an independent predictor of a low colon cancer-specific mortality, while BRAF mutation is associated with a high colon cancerThe relation between CIMP and lower mortality appeared to be consistent across all stages. Expand
Vitamin E consumption and the risk of coronary heart disease in men.
- E. Rimm, M. Stampfer, A. Ascherio, E. Giovannucci, G. Colditz, W. Willett
- The New England journal of medicine
- 20 May 1993
Evidence is provided of an association between a high intake of vitamin E and a lower risk of coronary heart disease in men, and public policy recommendations with regard to the use ofitamin E supplements should await the results of additional studies. Expand