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peginterferon alfa-2b

Known as: Pegylated Interferon Alpha-2b, Polyethylene Glycol IFN-A2b, PEG-IFN-a 2b 
A covalent conjugate of recombinant interferon alpha, subtype 2b, and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent. The… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Review
2012
Review
2012
  • Y. Barenholz
  • Journal of Controlled Release
  • 2012
  • Corpus ID: 20734524
Highly Cited
2009
Highly Cited
2009
BACKGROUND Treatment guidelines recommend the use of peginterferon alfa-2b or peginterferon alfa-2a in combination with ribavirin… 
Highly Cited
2008
Highly Cited
2008
It is known that many potent, often aromatic drugs are water insoluble, which has hampered their use for disease treatment. In… 
Highly Cited
2005
Highly Cited
2005
The incidence of hepatocellular carcinoma (HCC) has increased worldwide and is now the 5th most frequent cancer representing… 
Highly Cited
2004
Highly Cited
2004
BACKGROUND Treatment with pegylated interferon (peginterferon) and ribavirin for 48 weeks is more effective than conventional… 
Highly Cited
1998
Highly Cited
1998
BACKGROUND Only 15 to 20 percent of patients with chronic hepatitis C have a sustained virologic response to interferon therapy… 
Highly Cited
1994
Highly Cited
1994
Mice lacking the known subunit of the type I interferon (IFN) receptor were completely unresponsive to type I IFNs, suggesting… 
Highly Cited
1991
Highly Cited
1991
IL-10 inhibits the ability of macrophage but not B cell APC to stimulate cytokine synthesis by Th1 T cell clones. In this study…