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peginterferon alfa-2b

Known as: Pegylated Interferon Alpha-2b, Polyethylene Glycol IFN-A2b, PEG-IFN-a 2b 
A covalent conjugate of recombinant interferon alpha, subtype 2b, and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent. The… 
National Institutes of Health

Related topics

Related topics

43 relations
Acquired Immunodeficiency SyndromeAge related macular degenerationAutoimmune DiseasesBrain Neoplasms

Broader (5)

Antiviral AgentsInterferon-alphaPolyethylene GlycolsRecombinant Proteins

Narrower (2)

PegintronSylatron

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Ketal cross-linked poly(ethylene glycol)-poly(amino acid)s copolymer micelles for efficient intracellular delivery of doxorubicin.
A biocompatible, robust polymer micelle bearing pH-hydrolyzable shell cross-links was developed for efficient intracellular… 
Highly Cited
2011
Highly Cited
2011
IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection
Polymorphisms near the IL28B gene, which code for interferon (IFN)‐λ3, predict response to pegylated interferon‐α (PEG‐IFN) and… 
Highly Cited
2007
Highly Cited
2007
pH- and temperature-sensitive, injectable, biodegradable block copolymer hydrogels as carriers for paclitaxel.
Review
2006
Review
2006
IFN-lambda: novel antiviral cytokines.
The first line of defense against viral infections is mediated by interferons (IFN)s, which are produced rapidly by the infected… 
Highly Cited
2004
Highly Cited
2004
Development of acrylic-based copolymers for oral insulin delivery.
Highly Cited
2003
Highly Cited
2003
Site-specific PEGylation of a lysine-deficient TNF-α with full bioactivity
Addition of polyethylene glycol to protein (PEGylation) to improve stability and other characteristics is mostly nonspecific and… 
Highly Cited
2003
Highly Cited
2003
Local Delivery of CpG Oligodeoxynucleotides Induces Rapid Changes in the Genital Mucosa and Inhibits Replication, but Not Entry, of Herpes Simplex Virus Type 2
ABSTRACT Mucosal surfaces are the entry sites for the vast majority of infectious pathogens and provide the first line of defense… 
Review
2002
Review
2002
Paramyxovirus strategies for evading the interferon response
Two genera, the Respirovirus (Sendai virus (SeV) and human parainfluenza virus (hPIV3) and the Rubulavirus (simian virus (SV) 5… 
Highly Cited
2002
Highly Cited
2002
Amphiphilic Telechelics Incorporating Polyhedral Oligosilsesquioxane: 1. Synthesis and Characterization
Well-defined amphiphilic telechelics incorporating polyhedral oligosilsesquioxane (POSS) were synthesized by direct urethane… 
Highly Cited
1998
Highly Cited
1998
The Reactive Polymeric Micelle Based on An Aldehyde-Ended Poly(ethylene glycol)/Poly(lactide) Block Copolymer
Formation of amphiphilic poly(ethylene glycol)-b-polylactide (PEG/PLA) block copolymers was accomplished by using potassium… 
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