Skip to search formSkip to main contentSkip to account menu

peginterferon alfa-2b

Known as: Pegylated Interferon Alpha-2b, Polyethylene Glycol IFN-A2b, PEG-IFN-a 2b 
A covalent conjugate of recombinant interferon alpha, subtype 2b, and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent. The… 
National Institutes of Health

Related topics

Related topics

43 relations
Acquired Immunodeficiency SyndromeAge related macular degenerationAutoimmune DiseasesBrain Neoplasms

Broader (5)

Antiviral AgentsInterferon-alphaPolyethylene GlycolsRecombinant Proteins

Narrower (2)

PegintronSylatron

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C
Chronic infection with the hepatitis C virus (HCV) affects 170 million people worldwide and is an important cause of liver… 
Highly Cited
2006
Highly Cited
2006
Extended treatment duration for hepatitis C virus type 1: comparing 48 versus 72 weeks of peginterferon-alfa-2a plus ribavirin.
BACKGROUND & AIMS The treatment of patients infected with hepatitis C virus (HCV) type 1 remains a challenge necessitating… 
Review
2006
Review
2006
Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors.
Induction of type I interferons (IFNs) by viruses and other pathogens is crucial for innate immunity, and it is mediated by the… 
Highly Cited
2005
Highly Cited
2005
Regulation of hepcidin transcription by interleukin-1 and interleukin-6.
Hepcidin is a peptide that regulates iron homeostasis by inhibiting iron absorption by the small intestine and release of iron… 
Highly Cited
2002
Highly Cited
2002
Effects of cloud-point grafting, chain length, and density of PEG layers on competitive adsorption of ocular proteins.
Highly Cited
2001
Highly Cited
2001
Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology
We show here that mouse interferon-α (IFN-α)–producing cells (mIPCs) are a unique subset of immature antigen-presenting cells… 
Highly Cited
2000
Highly Cited
2000
Doxorubicin-loaded poly(ethylene glycol)-poly(beta-benzyl-L-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance.
Highly Cited
1996
Highly Cited
1996
Characterization of early IL-12, IFN-alphabeta, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infection.
Murine cytomegalovirus (MCMV) infection of mice induces early cytokines. Although certain of these can directly inhibit viral… 
Highly Cited
1995
Highly Cited
1995
Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins.
Activation of early response genes by interferons (IFNs) requires tyrosine phosphorylation of STAT (signal transducers and… 
Highly Cited
1990
Highly Cited
1990
Liposomes for the sustained drug release in vivo.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)