Skip to search formSkip to main contentSkip to account menu

peginterferon alfa-2b

Known as: Pegylated Interferon Alpha-2b, Polyethylene Glycol IFN-A2b, PEG-IFN-a 2b 
A covalent conjugate of recombinant interferon alpha, subtype 2b, and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent. The… 
National Institutes of Health

Related topics

Related topics

43 relations
Acquired Immunodeficiency SyndromeAge related macular degenerationAutoimmune DiseasesBrain Neoplasms

Broader (5)

Antiviral AgentsInterferon-alphaPolyethylene GlycolsRecombinant Proteins

Narrower (2)

PegintronSylatron

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
A virus-mimetic nanogel vehicle.
Viruses infect specific cells within host organisms, replicate, destroy the cells, and spread from cell to cell in infectious… 
Highly Cited
2004
Highly Cited
2004
Peginterferon Alfa-2b Plus Ribavirin for the Treatment of Chronic Hepatitis C Genotype 4
BACKGROUND:The hepatitis C virus (HCV) genotype is an important predictive parameter for the success of pegylated interferon plus… 
Highly Cited
2003
Highly Cited
2003
Site-specific PEGylation of a lysine-deficient TNF-α with full bioactivity
Addition of polyethylene glycol to protein (PEGylation) to improve stability and other characteristics is mostly nonspecific and… 
Highly Cited
2003
Highly Cited
2003
Local Delivery of CpG Oligodeoxynucleotides Induces Rapid Changes in the Genital Mucosa and Inhibits Replication, but Not Entry, of Herpes Simplex Virus Type 2
ABSTRACT Mucosal surfaces are the entry sites for the vast majority of infectious pathogens and provide the first line of defense… 
Highly Cited
2001
Highly Cited
2001
Galactosylated chitosan-graft-poly(ethylene glycol) as hepatocyte-targeting DNA carrier.
Highly Cited
2000
Highly Cited
2000
Superconformal Electrodeposition of Copper in 500–90 nm Features
Superconformal electrodeposition of copper in 500 nm deep trenches ranging from 500 to 90 nm in width has been demonstrated using… 
Highly Cited
1998
Highly Cited
1998
Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIV-vaccinia challenge.
Mucosal tissues are major sites of HIV entry and initial infection. Thus, the induction of a mucosal cytotoxic T lymphocyte (CTL… 
Highly Cited
1998
Highly Cited
1998
The Reactive Polymeric Micelle Based on An Aldehyde-Ended Poly(ethylene glycol)/Poly(lactide) Block Copolymer
Formation of amphiphilic poly(ethylene glycol)-b-polylactide (PEG/PLA) block copolymers was accomplished by using potassium… 
Highly Cited
1996
Highly Cited
1996
Vaccination with syngeneic, lymphoma-derived immunoglobulin idiotype combined with granulocyte/macrophage colony-stimulating factor primes mice for a protective T-cell response.
The idiotype of the Ig expressed by a B-cell malignancy (Id) can serve as a unique tumor-specific antigen and as a model for… 
Highly Cited
1990
Highly Cited
1990
The human intracellular Mx‐homologous protein is specifically induced by type I interferons
The murine Mx‐1 protein is one of the best biochemically and functionally characterized interferon (IFN)‐induced proteins that is… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)