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Autoimmune Diseases

Known as: Autoimmune disease NOS, Disease, Autoimmune, Autoimmune disorders 
A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of… 
National Institutes of Health

Related topics

Related topics

49 relations
AUTOANTIBODY RESPONSEAUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE IIIAnkylosing spondylitisAutoantigens

Narrower (14)

Antiphospholipid SyndromeAutoimmune hemolytic anemiaAutoimmune thyroid diseaseAutoimmune thyroiditis

Broader (1)

manifestations of immunopathology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
HMGB1: A multifunctional alarmin driving autoimmune and inflammatory disease
HMGB1 is a non-histone nuclear protein that can serve as an alarmin to drive the pathogenesis of inflammatory and autoimmune… 
Review
2010
Review
2010
Mechanisms of impaired regulation by CD4+CD25+FOXP3+ regulatory T cells in human autoimmune diseases
A lack of regulatory T (TReg) cells that express CD4, CD25 and forkhead box P3 (FOXP3) results in severe autoimmunity in both… 
Highly Cited
2000
Highly Cited
2000
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
B cells are important in the development of autoimmune disorders by mechanisms involving disregulated polyclonal B-cell… 
Highly Cited
1997
Highly Cited
1997
An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is the only described systemic autoimmune disease with… 
Highly Cited
1997
Highly Cited
1997
A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease.
A novel polymorphism in the extracellular domain 2 (EC2) of FcgammaRIIIA affects ligand binding by natural killer (NK) cells and… 
Highly Cited
1994
Highly Cited
1994
Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis.
Experimental autoimmune encephalomyelitis (EAE) is a cell-mediated autoimmune disease that serves as an animal model for multiple… 
Highly Cited
1991
Highly Cited
1991
Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease.
The biological functions of the BCL2 gene were investigated in transgenic mice harboring human BCL2 cDNA under the control of an… 
Highly Cited
1990
Highly Cited
1990
Autoimmune diseases: the failure of self tolerance.
The ability to discriminate between self and nonself antigens is vital to the functioning of the immune system as a specific… 
Highly Cited
1985
Highly Cited
1985
Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a…
Organ-specific autoimmune diseases such as oophoritis, gastritis, thyroiditis, and orchitis were induced in female or male nude… 
Highly Cited
1974
Highly Cited
1974
Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies.
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