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Autoantigens

Known as: Self-Antigens, Autoantigens [Chemical/Ingredient], Autoantigen 
An endogenous antigen that stimulates the production of autoantibodies, as in an autoimmune reaction. Autoantigens are proteins, nucleic acids, or… 
National Institutes of Health

Related topics

Related topics

40 relations

Narrower (31)

AM antigenAsrgl1 protein, ratCB antigen, nuclearCDR1 protein, human

Broader (1)

Antigens
Antigens, NuclearAutoimmune DiseasesAutoimmune reactionAutoimmune state

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Cd4+Cd25+ regulatory T cells and their therapeutic potential.
The human immune system mounts specific responses to a vast array of antigens. Although this is clearly beneficial in fighting… 
Review
2003
Review
2003
Oral tolerance
Autoimmune conditions caused by injurious immune responses against self-antigens can be ameliorated if the inappropriate… 
Highly Cited
2003
Highly Cited
2003
CD4 T cell activation by myelin oligodendrocyte glycoprotein is suppressed by adult but not cord blood CD25+ T cells
Regulatory T cells expressing CD25 have been shown to protect rodents from organ‐specific autoimmune diseases. Similar CD25… 
Review
1998
Review
1998
Stem cell transplantation for severe autoimmune diseases: progress and problems.
Since Morton and Siegel's epochal experiments 30 years ago animal models have been successfully utilized both for transfer and… 
Highly Cited
1996
Highly Cited
1996
Breaking self-tolerance in nonobese diabetic mice
Unresponsiveness to self is maintained through two mechanisms of immune regulation: thymic-negative selection and peripheral… 
Review
1983
Review
1983
Cellular mechanisms of immunologic tolerance.
Immunologic tolerance, the phenomenon whereby antigen interacts with the lymphoid system to impair its later capacity to respond… 
Highly Cited
1978
Highly Cited
1978
High proportion of Ig-producing cells making autoantibody in normal mice
‘NATURAL’ serum antibodies are thought to arise as a result of stimulation by environmental antigens. Evidence suggests, however… 
Highly Cited
1977
Highly Cited
1977
Killer cells reactive to altered-self antigens can also be alloreactive.
Murine cytotoxic thymus-derived lymphocytes immunized against cells bearing foreign minor histocompatibility antigens are… 
Highly Cited
1974
Highly Cited
1974
Large numbers of cells in normal mice produce antibody components of isologous erythrocytes
THERE are a number of arguments against the idea1 that self-tolerance depends on a purge of all self-reactive clones early in… 
Highly Cited
1973
Highly Cited
1973
REGULATION OF AUTOSENSITIZATION
We studied the mechanisms underlying the natural tolerance of thymus-derived (T) lymphocytes for self-antigens. Lymphocytes from… 
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