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Interferon-alpha

Known as: IFN-A, alpha-interferon, Interferon.alpha 
One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Interferon-alpha (IFN-α) is a potent anti-viral cytokine, critical to the host immune response against viruses. IFN-α is first… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Since sunitinib malate has shown activity in two uncontrolled studies in patients with metastatic renal-cell carcinoma… Expand
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Highly Cited
2006
Highly Cited
2006
The structural basis for the distinction of viral RNA from abundant self RNA in the cytoplasm of virally infected cells is… Expand
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Highly Cited
2005
Highly Cited
2005
Many aspects of the hepatitis C virus (HCV) life cycle have not been reproduced in cell culture, which has slowed research… Expand
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Highly Cited
2004
Highly Cited
2004
Double-stranded ribonucleic acid (dsRNA) serves as a danger signal associated with viral infection and leads to stimulation of… Expand
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Review
2004
Review
2004
Summary.  Hepatitis B virus (HBV) infection is a serious global health problem, with 2 billion people infected worldwide, and 350… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high response rates in patients with chronic… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND BCR-ABL is a constitutively activated tyrosine kinase that causes chronic myeloid leukemia (CML). Since tyrosine… Expand
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Highly Cited
1998
Highly Cited
1998
To better understand the dynamics of hepatitis C virus and the antiviral effect of interferon-alpha-2b (IFN), viral decline in 23… Expand
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Highly Cited
1986
Highly Cited
1986
We treated 10 patients who had chronic non-A,non-B hepatitis with recombinant human alpha interferon in varying doses (0.5 to 5… Expand
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