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Interferon-alpha

Known as: IFN-A, alpha-interferon, Interferon.alpha 
One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
BACKGROUND Since sunitinib malate has shown activity in two uncontrolled studies in patients with metastatic renal-cell carcinoma… Expand
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Highly Cited
2006
Highly Cited
2006
The structural basis for the distinction of viral RNA from abundant self RNA in the cytoplasm of virally infected cells is… Expand
Highly Cited
2005
Highly Cited
2005
Many aspects of the hepatitis C virus (HCV) life cycle have not been reproduced in cell culture, which has slowed research… Expand
Highly Cited
2004
Highly Cited
2004
Double-stranded ribonucleic acid (dsRNA) serves as a danger signal associated with viral infection and leads to stimulation of… Expand
Review
2004
Review
2004
  • D. Lavanchy
  • Journal of viral hepatitis
  • 2004
  • Corpus ID: 163757
Summary.  Hepatitis B virus (HBV) infection is a serious global health problem, with 2 billion people infected worldwide, and 350… Expand
Highly Cited
2003
Highly Cited
2003
BACKGROUND Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high response rates in patients with chronic… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND BCR-ABL is a constitutively activated tyrosine kinase that causes chronic myeloid leukemia (CML). Since tyrosine… Expand
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Highly Cited
1998
Highly Cited
1998
To better understand the dynamics of hepatitis C virus and the antiviral effect of interferon-alpha-2b (IFN), viral decline in 23… Expand
Review
1994
Review
1994
  • J. Gutterman
  • Proceedings of the National Academy of Sciences…
  • 1994
  • Corpus ID: 2490970
Cytokines are soluble proteins that allow for communication between cells and the external environment. Interferon (IFN) alpha… Expand
Highly Cited
1986
Highly Cited
1986
We treated 10 patients who had chronic non-A,non-B hepatitis with recombinant human alpha interferon in varying doses (0.5 to 5… Expand
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