Interferon-alpha

Known as: IFN-A, alpha-interferon, Interferon.alpha 
One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates… (More)
National Institutes of Health

Related topics

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Narrower (23)

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Broader (2)

Immunologic FactorsInterferons

Papers overview

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Review
2017
Review
2017
Diabetes mellitus, insulin resistance and hepatitis C virus infection: A contemporary review
AIM To summarise the literature data on hepatitis C virus (HCV)-infected patients concerning the prevalence of glucose… (More)
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Highly Cited
2010
Highly Cited
2010
Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206.
PURPOSE Bevacizumab is an antibody that binds vascular endothelial growth factor and has activity in metastatic renal cell… (More)
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Highly Cited
2009
Highly Cited
2009
MicroRNA expression, survival, and response to interferon in liver cancer.
BACKGROUND Hepatocellular carcinoma is a common and aggressive cancer that occurs mainly in men. We examined microRNA expression… (More)
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Highly Cited
2008
Highly Cited
2008
Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206.
PURPOSE Bevacizumab is an antibody that binds to vascular endothelial growth factor (VEGF) and has activity in metastatic renal… (More)
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Highly Cited
2007
Highly Cited
2007
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma.
BACKGROUND Since sunitinib malate has shown activity in two uncontrolled studies in patients with metastatic renal-cell carcinoma… (More)
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Highly Cited
2003
Highly Cited
2003
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia.
BACKGROUND Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high response rates in patients with chronic… (More)
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Highly Cited
2002
Highly Cited
2002
Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma.
PURPOSE To define outcome data and prognostic criteria for patients with metastatic renal cell carcinoma (RCC) treated with… (More)
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Highly Cited
2001
Highly Cited
2001
Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.
Dendritic cells (DCs) are important in regulating both immunity and tolerance. Hence, we hypothesized that systemic lupus… (More)
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Highly Cited
1998
Highly Cited
1998
Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy.
To better understand the dynamics of hepatitis C virus and the antiviral effect of interferon-alpha-2b (IFN), viral decline in 23… (More)
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Highly Cited
1998
Highly Cited
1998
Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7.
Interferon (IFN) genes are among the earliest transcriptional responses to virus infection of mammalian cells. Although the… (More)
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