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Interferon-alpha

Known as: IFN-A, alpha-interferon, Interferon.alpha 
One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates… 
National Institutes of Health

Related topics

Related topics

46 relations

Narrower (23)

Alferon NDAI protocolIFNA13 protein, humanIFNA7 protein, human
Antineoplastic AgentsIFNA1 geneIFNA17 geneIFNA2 gene

Broader (2)

Immunologic FactorsInterferons

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Natural Alpha Interferon-Producing Cells Respond to Human Immunodeficiency Virus Type 1 with Alpha Interferon Production and Maturation into Dendritic Cells
ABSTRACT Natural alpha interferon (IFN-α)-producing cells (IPCs) are now recognized as identical to plasmacytoid dendritic cell… 
Highly Cited
2002
Highly Cited
2002
Follow-up of complete cytogenetic remission in patients with chronic myeloid leukemia after cessation of interferon alfa.
PURPOSE A small proportion of patients with chronic myeloid leukemia (CML) achieve a complete cytogenetic response (CCR), defined… 
Highly Cited
2000
Highly Cited
2000
Intratumoral injection of dendritic cells derived in vitro in patients with metastatic cancer
Dendritic cells (DCs) are potent initiators of immune responses, and the infiltration of DCs into tumors may confer an improved… 
Highly Cited
2000
Highly Cited
2000
Interferon-based adjuvant chemoradiation therapy improves survival after pancreaticoduodenectomy for pancreatic adenocarcinoma.
Highly Cited
1998
Highly Cited
1998
Hepatitis C virus dynamics in vivo: Effect of ribavirin and interferon alfa on viral turnover
Treatment of patients with chronic hepatitis C with recombinant interferon alfa (rIFN‐α) can cause a decrease of serum… 
Highly Cited
1995
Highly Cited
1995
Simple fluorescent enzyme immunoassay for detection and quantification of hepatitis C viremia.
Highly Cited
1995
Highly Cited
1995
Lack of benefit of escalating dosage of interferon alfa in patients with chronic hepatitis C.
Highly Cited
1994
Highly Cited
1994
Comparative efficacy of interferon alfa in cirrhotic and noncirrhotic patients with non-A, non-B, C hepatitis. Le Groupe Français pour l'Etude du Traitement des Hépatites Chroniques NANB/C.
Highly Cited
1986
Highly Cited
1986
Requirement for HLA-DR+ accessory cells in natural killing of cytomegalovirus-infected fibroblasts
The role of HLA-DR+ cells in NK activity against CMV-infected FS4 foreskin fibroblasts and K562 erythroleukemia cells was… 
Highly Cited
1982
Highly Cited
1982
Effects of SV40 transformation on the cytoskeleton and behavioural properties of human keratinocytes.
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