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Interferons
Known as:
IFN
, Interferon
, Interferons [Chemical/Ingredient]
Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit…
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National Institutes of Health
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Related topics
Related topics
47 relations
Acquired Immunodeficiency Syndrome
Adaptive Immunity
Age related macular degeneration
Autoimmune Diseases
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Broader (3)
Antineoplastic Agents
Lymphokines
Proteins
Narrower (9)
Interferon Alfa-2b
Interferon Type II
Interferon-alpha
Interferon-beta
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Interferon-Stimulated Genes: What Do They All Do?
J. Schoggins
Annual Review of Virology
2019
Corpus ID: 195844135
In the absence of an intact interferon (IFN) response, mammals may be susceptible to lethal viral infection. IFNs are secreted…
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Review
2013
Review
2013
Regulation of type I interferon responses
L. Ivashkiv
,
L. Donlin
Nature reviews. Immunology
2013
Corpus ID: 28889149
Type I interferons (IFNs) activate intracellular antimicrobial programmes and influence the development of innate and adaptive…
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Review
2011
Review
2011
Interferon-stimulated genes and their antiviral effector functions
J. Schoggins
,
C. Rice
Current Opinion in Virology
2011
Corpus ID: 20129294
Highly Cited
2008
Highly Cited
2008
Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity
Daniel B. Stetson
,
J. S. Ko
,
T. Heidmann
,
R. Medzhitov
Cell
2008
Corpus ID: 3752751
Review
2007
Review
2007
Interferons at age 50: past, current and future impact on biomedicine
E. Borden
,
G. Sen
,
+4 authors
G. Stark
Nature reviews. Drug discovery
2007
Corpus ID: 583709
The family of interferon (IFN) proteins has now more than reached the potential envisioned by early discovering virologists: IFNs…
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Review
2006
Review
2006
Interferons, immunity and cancer immunoediting
G. Dunn
,
Catherine M. Koebel
,
R. Schreiber
Nature reviews. Immunology
2006
Corpus ID: 223082
A clear picture of the dynamic relationship between the host immune system and cancer is emerging as the cells and molecules that…
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Highly Cited
2004
Highly Cited
2004
TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function.
A. Krug
,
A. French
,
+7 authors
M. Colonna
Immunity
2004
Corpus ID: 315257
Review
2001
Review
2001
Viruses and interferons.
G. Sen
Annual Review of Microbiology
2001
Corpus ID: 29251044
The interferon system is the first line of defense against viral infection in mammals. This system is designed to block the…
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Highly Cited
1997
Highly Cited
1997
Selective Expression of an Interleukin-12 Receptor Component by Human T Helper 1 Cells
L. Rogge
,
L. Barberis-Maino
,
+4 authors
F. Sinigaglia
Journal of Experimental Medicine
1997
Corpus ID: 2832418
Highly Cited
1996
Highly Cited
1996
Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease
J. Durbin
,
Renée Hackenmiller
,
M. Simon
,
D. Levy
Cell
1996
Corpus ID: 14652347
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