Skip to search formSkip to main contentSkip to account menu

Interferons

Known as: IFN, Interferon, Interferons [Chemical/Ingredient] 
Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit… 
National Institutes of Health

Related topics

Related topics

47 relations
Acquired Immunodeficiency SyndromeAdaptive ImmunityAge related macular degenerationAutoimmune Diseases

Broader (3)

Antineoplastic AgentsLymphokinesProteins

Narrower (9)

Interferon Alfa-2bInterferon Type IIInterferon-alphaInterferon-beta

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1983
1983
Limiting dilution analysis of the frequency of human T cells and large granular lymphocytes proliferating in response to interleukin 2. II. Regulatory role of interferon on proliferative and…
Limiting dilution analysis has shown that large granular lymphocytes (LGL) and small T cells undergo proliferation in response to… 
Highly Cited
1983
Highly Cited
1983
Studies on the mechanism of natural killer cell-mediated cytotoxicity. IV. Interferon-induced inhibition of NK target cell susceptibility to lysis is due to a defect in their ability to stimulate…
The effects of interferon (IFN) at the level of the target cell in the natural killer cytotoxic factors (NKCF) system have been… 
Highly Cited
1982
Highly Cited
1982
Endogenous and interferon-augmented natural killer cell activity of human peripheral blood mononuclear cells in vitro. Studies of patients with multiple sclerosis, systemic lupus erythematosus or…
Peripheral blood mononuclear cells (PBMC) of normal human donors are spontaneously cytotoxic for certain tumour-derived and virus… 
1982
1982
Ontogeny of Nk-1+ natural killer cells. I. Promotion of Nk-1+ cells in fetal, baby, and old mice.
Using anti-Nk-1.1 serum, the alloantiserum specific for murine natural killer (NK) cells, we followed the ontogenetic development… 
Highly Cited
1977
Highly Cited
1977
Studies of L cells persistently infected with VSV: factors involved in the regulation of persistent infection.
Infection of interferon-treated L cells with VSV led frequently to the establishment of L cells persistently infected with VSV… 
1976
1976
Human fibroblast and leukocyte interferons show different dose-response curves in assay of cell protection.
Preparations of human fibroblast and leukocyte interferons of similar potency show markedly different dose-response curves in an… 
1973
1973
Mechanism of interferon uptake in parental and somatic monkey-mouse hybrid cells.
Dose-response curves of interferons in different sensitive cells are regularly sigmoidal. In somatic monkey-mouse hybrid cells… 
1967
1967
Characterization of Virus- and Endotoxin-induced Interferons Obtained from the Serum and Urine of Rabbits
Interferons induced in the rabbit by Newcastle disease virus or by endotoxin have been further characterized as to their… 
1963
1963
STUDIES ON THE SPECIFICITY OF INTERFERON.
SUMMARY: The antiviral effects of chick and mouse interferons on chick and mouse cells were studied. In both systems a small… 
1963
1963
Cellular resistance to viral infection, with particular reference to endogenous interferon.
GENERAL CONSIDERATIONS..................................................................... 72 VIRAL INTERFERENCE… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)