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Interferon Type II

Known as: Interferon gamma (human lymphocyte protein moiety reduced), gamma interferons, gammas interferon 
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (5)

ActimmuneInterferon gamma-1bMuIFN-gamma (95-133)Tsc2 Angiomyolipomas, Renal, Modifier Of
Adaptive ImmunityAldesleukinAutophagy Regulation PathwayChemokine CXCL10

Broader (3)

Antineoplastic AgentsAntiviral AgentsInterferons

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1998
Highly Cited
1998
The IL-4 rapidly produced in BALB/c mice after infection with Leishmania major down-regulates IL-12 receptor beta 2-chain expression on CD4+ T cells resulting in a state of unresponsiveness to IL-12.
Within 1 day of infection with Leishmania major, susceptible BALB/c mice produce a burst of IL-4 in their draining lymph nodes… 
Highly Cited
1998
Highly Cited
1998
Resistance to the African trypanosomes is IFN-gamma dependent.
The role of variant surface glycoprotein (VSG)-specific Th cell responses in determining resistance to the African trypanosomes… 
Highly Cited
1997
Highly Cited
1997
Induction and prevention of colonic inflammation in IL-2-deficient mice.
Gene-targeted mice deficient for IL-2 (IL-2 -/- mice) are free of apparent disease when maintained under germfree conditions but… 
Highly Cited
1995
Highly Cited
1995
Bayesian Learning for Neural Networks
Artificial "neural networks" are widely used as flexible models for classification and regression applications, but questions… 
Highly Cited
1992
Highly Cited
1992
Th1 lymphokine production profiles of nickel-specific CD4+T-lymphocyte clones from nickel contact allergic and non-allergic individuals.
Panels of nickel-specific T-lymphocyte clones (TLC) were prepared from nickel-allergic and non-allergic donors. TLC from both… 
Highly Cited
1992
Highly Cited
1992
Aqueous antigens induce in vivo tolerance selectively in IL-2- and IFN-gamma-producing (Th1) cells.
As a model for understanding in vivo immune responses, we have exposed mice to aqueous haptenated-protein Ag, and examined immune… 
Highly Cited
1991
Highly Cited
1991
Th1 and Th2 cytokine secretion patterns in murine candidiasis: association of Th1 responses with acquired resistance
Two chemically mutagenized agerminative variants of Candida albicans were used to immunize mice against challenge with highly… 
Highly Cited
1989
Highly Cited
1989
High interleukin-6 serum levels and increased production by leucocytes in alcoholic liver cirrhosis. Correlation with IgA serum levels and lymphokines production.
Hypergammaglobulinaemia and enhanced serum IgA levels are common in alcoholic liver cirrhosis. Interleukin-6 (IL-6), which is… 
Highly Cited
1988
Highly Cited
1988
The relationship between infiltrating CD4+ lymphocytes, activated eosinophils, and the magnitude of the allergen-induced late phase cutaneous reaction in man.
The phenotype and activation status of leukocytes infiltrating human late phase allergic skin reactions were investigated by… 
Highly Cited
1980
Highly Cited
1980
Characterization of protein kinase activity associated with the transforming gene product of Fujinami sarcoma virus
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