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Chemokine CXCL10

Known as: Small Inducible Cytokine B10, Cytokine IP 10 Protein, gammaIP-10 Protein 
A CXC chemokine that is induced by GAMMA-INTERFERON and is chemotactic for MONOCYTES and T-LYMPHOCYTES. It has specificity for the CXCR3 RECEPTOR.
National Institutes of Health

Related topics

Related topics

19 relations

Broader (3)

CXCL10 genechemokinecytokine

Narrower (1)

CXCL10 protein, human
CXCR3 geneCXCR3 wt AlleleChemokine (C-X-C Motif) Ligand 10 MeasurementGrowth Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Increase of interferon‐γ‐inducible CXC chemokine CXCL10 serum levels in patients with active Graves’ disease, and modulation by methimazole therapy
Background  CXCL10 plays an important role in the initial phases of Graves’ disease (GD) and autoimmune thyroiditis (AT); however… 
Highly Cited
2003
Highly Cited
2003
Effect of Anti-CXCL10 Monoclonal Antibody on Herpes Simplex Virus Type 1 Keratitis and Retinal Infection
ABSTRACT The inflammatory response to acute ocular herpes simplex virus type 1 (HSV-1) infection in mice involves the innate and… 
Highly Cited
2003
Highly Cited
2003
Expression of the chemokine IP‐10 correlates with the accumulation of hepatic IFN‐γ and IL‐18 mRNA in chronic hepatitis C but not in hepatitis B
The pathogenesis of hepatitis C virus‐induced chronic liver disease is still poorly understood. Previous studies revealed… 
Highly Cited
2002
Highly Cited
2002
Leukocyte Infiltration, But Not Neurodegeneration, in the CNS of Transgenic Mice with Astrocyte Production of the CXC Chemokine Ligand 101
The CXC chemokine ligand (CXCL)10 is induced locally in the CNS in diverse pathologic states. The impact of CXCL10 production in… 
Highly Cited
2001
Highly Cited
2001
Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin.
Interleukin (IL)-13 is a central mediator of the processes underlying the induction of airways hyperreactivity (AHR) in the… 
Highly Cited
2001
Highly Cited
2001
Adenovirus-mediated delivery of antiangiogenic genes as an antitumor approach
Based on the observation that the growth of solid tumors is dependent on the formation of new blood vessels, therapeutic… 
Highly Cited
2001
Highly Cited
2001
Preferential Th1 profile of T helper cell responses in X‐linked (Bruton′s) agammaglobulinemia
X‐linked agammaglobulinemia (XLA) is a primary immunodeficiency of the B‐cell compartment caused by a defective gene encoding for… 
Highly Cited
2000
Highly Cited
2000
Expression of Chemokine Genes in Murine Macrophages Infected with Orientia tsutsugamushi
ABSTRACT Scrub typhus, caused by Orientia tsutsugamushiinfection, is characterized by local as well as systemic inflammatory… 
Highly Cited
1998
Highly Cited
1998
Human IP-10 selectively promotes dominance of polyclonally activated and environmental antigen-driven IFN-gamma over IL-4 responses.
Human interferon-inducible protein 10 (IP-10) differs from most chemokines in its apparent specificity for activated T… 
1998
1998
IP-10 gene transcription by virus in astrocytes requires cooperation of ISRE with adjacent kappaB site but not IRF-1 or viral transcription.
Transcription of the IP-10 gene requires interferon (IFN)-stimulated response element (ISRE) and kappaB sites to be induced by… 
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