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CXCL10 protein, human

Known as: Small Inducible Cytokine B10, Protein 10 from Interferon (Gamma)-Induced Cell Line, Interferon-Inducible Cytokine IP-10 
C-X-C motif chemokine 10 (98 aa, ~11 kDa) is encoded by the human CXCL10 gene. This protein is involved in chemotaxis of monocytes and T-lymphocytes.
National Institutes of Health

Related topics

Related topics

22 relations
Biologic DevelopmentCXCL10 geneCXCL10 wt AlleleCell Adhesion

Broader (1)

Chemokine CXCL10

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Quantitation of pretreatment serum interferon‐γ–inducible protein‐10 improves the predictive value of an IL28B gene polymorphism for hepatitis C treatment response
Polymorphisms of the IL28B gene are highly associated with sustained virological response (SVR) in patients with chronic… 
Highly Cited
2009
Highly Cited
2009
Absence of a classically activated macrophage cytokine signature in peripheral spondylarthritis, including psoriatic arthritis.
OBJECTIVE Peripheral spondylarthritis (SpA) is characterized by macrophages that express CD163, a marker of alternative… 
Highly Cited
2007
Highly Cited
2007
CXCL10-CXCR3 interactions play an important role in the pathogenesis of acute graft-versus-host disease in the skin following allogeneic stem-cell transplantation.
Acute graft-versus-host disease (aGVHD) remains a serious complication following allogeneic stem-cell transplantation (SCT), and… 
Highly Cited
2004
Highly Cited
2004
Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments.
The neutrophil-attracting chemokine interleukin 8 (IL-8) is stored in the Weibel-Palade body (WPB) of endothelial cells (ECs… 
Highly Cited
2004
Highly Cited
2004
Neuronal apoptosis is mediated by CXCL10 overexpression in simian human immunodeficiency virus encephalitis.
Highly Cited
2003
Highly Cited
2003
Pleiotropic effects of CXC chemokines in gastric carcinoma: differences in CXCL8 and CXCL1 expression between diffuse and intestinal types of gastric carcinoma
CXC chemokines modulate host immunity, neovascularization, growth and invasive behaviour of tumours. Despite their relevance in… 
Highly Cited
2003
Highly Cited
2003
Inhibition of IFN-γ-Inducible Protein-10 Abrogates Colitis in IL-10−/− Mice 1
A deficiency in understanding the steps responsible for colitis is the lack of comprehension for the role chemokines play in… 
Highly Cited
2000
Highly Cited
2000
Intratumoral Coinjection of Two Adenoviruses, One Encoding the Chemokine IFN-γ-Inducible Protein-10 and Another Encoding IL-12, Results in Marked Antitumoral Synergy1
We have constructed a recombinant defective adenovirus that expresses functional murine IFN-γ-inducible protein-10 (IP-10… 
Highly Cited
1998
Highly Cited
1998
Hyaluronan Fragments Synergize with Interferon-γ to Induce the C-X-C Chemokines Mig and Interferon-inducible Protein-10 in Mouse Macrophages*
Hallmarks of chronic inflammation and tissue fibrosis are increased influx of activated inflammatory cells, mediator release, and… 
Highly Cited
1995
Highly Cited
1995
The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation
IP-10 is a member of the chemokine family of cytokines and is induced in a variety of cells in response to interferon gamma and… 
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