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Interferon-beta

Known as: interferon beta natural, IFN-B, Beta Interferon 
One of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a… 
National Institutes of Health

Related topics

Related topics

40 relations

Broader (4)

Antineoplastic AgentsAntiviral AgentsImmunologic FactorsInterferons

Narrower (6)

AvonexBetaseronFiblaferonRebif
BG00001Biological Response ModifiersCytokine GeneCytokine Receptor Binding

Papers overview

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Highly Cited
2003
Highly Cited
2003
Microarray analysis identifies interferon β-regulated genes in multiple sclerosis
Highly Cited
1997
Highly Cited
1997
Intra- and intermolecular cooperative binding of high-mobility-group protein I(Y) to the beta-interferon promoter
The mammalian high-mobility-group protein I(Y) [HMG I(Y)], while not a typical transcriptional activator, is required for the… 
Highly Cited
1997
Highly Cited
1997
Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway
Activation of early response genes by interferons (IFNs) and other cytokines requires tyrosine phosphorylation of a family of… 
Highly Cited
1990
Highly Cited
1990
Growth inhibition of glioma cells transfected with the human beta-interferon gene by liposomes coupled with a monoclonal antibody.
A human beta-interferon (HuIFN-beta) gene inserted into a eukaryotic expression vector (pSV2IFN-beta) was entrapped in liposomes… 
Highly Cited
1988
Highly Cited
1988
Different induction patterns of mRNA for IFN-alpha and -beta in human mononuclear leukocytes after in vitro stimulation with herpes simplex virus-infected fibroblasts and Sendai virus.
Human peripheral blood mononuclear leukocytes (PBL) were stimulated in vitro by HSV type 1-infected glutaraldehyde-fixed… 
Highly Cited
1988
Highly Cited
1988
Interferon-beta 2/interleukin 6 is a co-stimulant for human T lymphocytes.
IFN-beta 2/IL-6 promotes the proliferation of human peripheral blood T cells in the presence of either PHA or Con A. This effect… 
Highly Cited
1987
Highly Cited
1987
Activity of interferons alpha, beta, and gamma against human immunodeficiency virus replication in vitro.
The antiviral activities of various interferon preparations against human immunodeficiency virus (HIV) were evaluated in vitro… 
Highly Cited
1982
Highly Cited
1982
Down-regulation of the interferon receptor.
Highly Cited
1981
Highly Cited
1981
Inhibitory effects of human leukocyte and fibroblast interferons on normal and chronic myelogenous leukemic granulocytic progenitor cells.
Inhibitory effects of two human interferon preparations, leukocyte interferon (Le-IF) and fibroblast interferon (F-IF), on… 
Highly Cited
1977
Highly Cited
1977
Is interferon tissue specific?- Effect of human leukocyte and fibroblast interferons on the growth of lymphoblastoid and osteosarcoma cell lines.
The growth inhibitory effect of human leukocyte and fibroblast interferons was tested in vitro. The effect of fibroblast… 
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