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Interferon-beta

Known as: interferon beta natural, IFN-B, Beta Interferon 
One of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a… Expand
National Institutes of Health

Related topics

Related topics

40 relations

Broader (4)

Antineoplastic AgentsAntiviral AgentsImmunologic FactorsInterferons

Narrower (6)

AvonexBetaseronFiblaferonRebif
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BG00001Biological Response ModifiersCytokine GeneCytokine Receptor Binding
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Subcutaneous Administration of Biotherapeutics: An Overview of Current Challenges and Opportunities
Subcutaneous delivery of biotherapeutics has become a valuable alternative to intravenous administration across many disease… Expand
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Review
2016
Review
2016
Treatment outcomes for patients with Middle Eastern Respiratory Syndrome Coronavirus (MERS CoV) infection at a coronavirus referral center in the Kingdom of Saudi Arabia
BackgroundMiddle Eastern Respiratory Syndrome coronavirus (MERS-CoV) is a poorly understood disease with no known treatments. We… Expand
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Highly Cited
2006
Highly Cited
2006
Natalizumab plus interferon beta-1a for relapsing multiple sclerosis.
BACKGROUND Interferon beta is used to modify the course of relapsing multiple sclerosis. Despite interferon beta therapy, many… Expand
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Highly Cited
2006
Highly Cited
2006
Inhibition of Retinoic Acid-Inducible Gene I-Mediated Induction of Beta Interferon by the NS1 Protein of Influenza A Virus
ABSTRACT The retinoic acid-inducible gene I product (RIG-I) has been identified as a cellular sensor of RNA virus infection… Expand
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Highly Cited
2000
Highly Cited
2000
Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. CHAMPS Study Group.
BACKGROUND Treatment with interferon beta has been shown to help patients with established multiple sclerosis, but it is not… Expand
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Highly Cited
2000
Highly Cited
2000
Influenza A Virus NS1 Protein Prevents Activation of NF-κB and Induction of Alpha/Beta Interferon
ABSTRACT The alpha/beta interferon (IFN-α/β) system represents one of the first lines of defense against virus infections. As a… Expand
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Highly Cited
1996
Highly Cited
1996
Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization
Vaccination with naked DNA elicits cellular and humoral immune responses that have a T helper cell type 1 bias. However, plasmid… Expand
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Highly Cited
1987
Highly Cited
1987
Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.
One of the oldest and most preserved of the homeostatic responses of the body to injury is the acute phase protein response… Expand
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Highly Cited
1983
Highly Cited
1983
Production of human beta interferon in insect cells infected with a baculovirus expression vector.
Autographa californica nuclear polyhedrosis virus (AcNPV) was used as an expression vector for human beta interferon. By using… Expand
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Highly Cited
1983
Highly Cited
1983
Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity
Human blood mononuclear leukocytes stimulated with toxoplasma antigen, concanavalin A, mezerein plus lentil lectin, or… Expand
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