Interferon-beta

Known as: interferon beta natural, IFN-B, Beta Interferon 
One of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
The retinoic acid-inducible gene I product (RIG-I) has been identified as a cellular sensor of RNA virus infection resulting in… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Interferon beta is used to modify the course of relapsing multiple sclerosis. Despite interferon beta therapy, many… (More)
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Highly Cited
2005
Highly Cited
2005
Viral infection or stimulation of TLR3 triggers signaling cascades, leading to activation of the transcription factors IRF-3 and… (More)
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Highly Cited
2005
Highly Cited
2005
Flaviviruses are insect-borne, positive-strand RNA viruses that have been disseminated worldwide. Their genome is translated into… (More)
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Highly Cited
2001
Highly Cited
2001
The immature plasmacytoid dendritic cell (PDC) is identical with the principal type I IFN-producing cell upon viral infection… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Treatment with interferon beta has been shown to help patients with established multiple sclerosis, but it is not… (More)
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Highly Cited
2000
Highly Cited
2000
The alpha/beta interferon (IFN-alpha/beta) system represents one of the first lines of defense against virus infections. As a… (More)
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Highly Cited
1998
Highly Cited
1998
  • Lancet
  • 1998
BACKGROUND The beneficial effects of interferon beta have only been shown for patients in the relapsing-remitting phase of… (More)
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Highly Cited
1987
Highly Cited
1987
One of the oldest and most preserved of the homeostatic responses of the body to injury is the acute phase protein response… (More)
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Highly Cited
1983
Highly Cited
1983
Human blood mononuclear leukocytes stimulated with toxoplasma antigen, concanavalin A, mezerein plus lentil lectin, or… (More)
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