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Interferon Alfa-2b

Known as: 2b alfa interferon, Interferon alfa 2b, Intron A 
A drug used to treat some infections caused by viruses and several types of cancer. These include hairy cell leukemia, melanoma, and follicular… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
BACKGROUND Treatment of HBeAg-positive patients with chronic hepatitis B is not effective in most. A combination of… Expand
Highly Cited
2004
Highly Cited
2004
CONTEXT Treatment of chronic hepatitis C virus (HCV) infection in human immunodeficiency virus (HIV)-infected patients is a… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Treatment with peginterferon alfa-2a alone produces significantly higher sustained virologic responses than treatment… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND & AIMS Liver fibrosis is an important prognostic factor in patients with hepatitis C. The effect of pegylated (PEG… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND A sustained virological response (SVR) rate of 41% has been achieved with interferon alfa-2b plus ribavirin therapy of… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The value of nephrectomy in metastatic renal-cell cancer has long been debated. Several nonrandomized studies suggest… Expand
Highly Cited
2001
Highly Cited
2001
BACKGROUND Depression commonly complicates treatment with the cytokine interferon alfa-2b. Laboratory animals pretreated with… Expand
Highly Cited
2000
Highly Cited
2000
PURPOSE Pivotal trial E1684 of adjuvant high-dose interferon alfa-2b (IFNalpha2b) therapy in high-risk melanoma patients… Expand
Highly Cited
1998
Highly Cited
1998
BACKGROUND Only 15 to 20 percent of patients with chronic hepatitis C have a sustained virologic response to interferon therapy… Expand
Highly Cited
1998
Highly Cited
1998
BACKGROUND Interferon alfa is the only effective treatment for patients with chronic hepatitis C. Forty percent of patients have… Expand
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