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Interferon Alfa-2b

Known as: 2b alfa interferon, Interferon alfa 2b, Intron A 
A drug used to treat some infections caused by viruses and several types of cancer. These include hairy cell leukemia, melanoma, and follicular… 
National Institutes of Health

Related topics

Related topics

46 relations
Acquired Immunodeficiency SyndromeAge related macular degenerationAutoimmune DiseasesCondylomata Acuminata

Narrower (3)

Heberon AlfaIntron ASch-30500

Broader (4)

IFNA2 protein, humanInterferon-alphaInterferonshuman leukocyte interferon

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Sustained virological response to antiviral therapy reduces mortality in HCV reinfection after liver transplantation.
Highly Cited
2000
Highly Cited
2000
Is an “à la carte” combination interferon alfa‐2b plus ribavirin regimen possible for the first line treatment in patients with chronic hepatitis C?
Randomized trials have shown the enhancement of efficacy with interferon alfa‐2b and ribavirin (IFN‐R) in comparison with… 
Highly Cited
1999
Highly Cited
1999
Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine…
Whether p38 and extracellular signal-regulated kinase (ERK) mitogen-activated protein kinase cascades are required for inducible… 
Review
1997
Review
1997
The growing family of interferon regulatory factors.
Highly Cited
1993
Highly Cited
1993
Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2
Interferon regulatory factor-1 (IRF-1), a transcriptional activator, and IRF-2, its antagonistic repressor, have been identified… 
Highly Cited
1990
Highly Cited
1990
Maintenance treatment with recombinant interferon alfa-2b in patients with multiple myeloma responding to conventional induction chemotherapy.
The use of interferon for the induction treatment of multiple myeloma has been shown to be effective in about 20 percent of… 
Review
1985
Review
1985
Immune interferon: a pleiotropic lymphokine with multiple effects.
Highly Cited
1984
Highly Cited
1984
Activation of human macrophages. Comparison of other cytokines with interferon-gamma
Cytokines affecting mononuclear phagocytes were screened for activation of human macrophages to secrete H2O2 and kill toxoplasmas… 
Highly Cited
1979
Highly Cited
1979
Augmentation of mouse natural killer cell activity by interferon and interferon inducers.
Interferon (IF), in addition to its anti-viral capacity, is increasingly being found to be a regulator of cell division, cell… 
Highly Cited
1976
Highly Cited
1976
Role of interferon in the pathogenesis of virus diseases in mice as demonstrated by the use of anti-interferon serum. II. Studies with herpes simplex, Moloney sarcoma, vesicular stomatitis, Newcastle…
The effect of potent sheep anti-mouse interferon globulin was investigated in several different experimental virus diseases of… 
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