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nisoxetine

Known as: 3-(2-methoxyphenoxy)-N-methyl-3-phenylpropylamine, 3-(o-methoxyphenoxy)-N-methyl-3-phenylpropylamine, N-methyl-gamma-(2-methylphenoxy)phenylpropanolamine 
 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Most antidepressants elicit their therapeutic benefits through selective blockade of Na+/Cl−-coupled neurotransmitter… Expand
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Highly Cited
2002
Highly Cited
2002
Selective blockers of the norepinephrine transporter (NET) inhibit dopamine uptake in the prefrontal cortex. This suggests that… Expand
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Highly Cited
2002
Highly Cited
2002
Cocaine blocks uptake by neuronal plasma membrane transporters for dopamine, serotonin and norepinephrine, producing subjective… Expand
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Highly Cited
2001
Highly Cited
2001
Parkinson's disease (PD) is characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta… Expand
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Highly Cited
1996
Highly Cited
1996
Nisoxetine is a potent and selective inhibitor of noradrenaline uptake into noradrenergic neurones. [3H]Nisoxetine binding to rat… Expand
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Highly Cited
1992
Highly Cited
1992
  • S. Tejani-Butt
  • The Journal of pharmacology and experimental…
  • 1992
  • Corpus ID: 7286251
The uptake sites for norepinephrine (NE) in brain have not been studied in much detail, probably due to the absence of an… Expand
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Highly Cited
1989
Highly Cited
1989
Specific binding sites for [3H]cocaine were identified in caudate-putamen membranes prepared from nonhuman primate brains (Macaca… Expand
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Highly Cited
1975
Highly Cited
1975
3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine (Lilly 110140) competitively inhibited the uptake of serotonin (5-HT… Expand
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Highly Cited
1974
Highly Cited
1974
Abstract Lilly 110140 is a highly selective inhibitor of serotonin uptake into synaptosomes of rat brain, unlike previous… Expand
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Highly Cited
1974
Highly Cited
1974
Summary Lilly 110140 is an inhibitor of serotonin uptake by brain synaptosomes. In rats, it had no effect on brain levels of… Expand
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