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nisoxetine

Known as: 3-(2-methoxyphenoxy)-N-methyl-3-phenylpropylamine, 3-(o-methoxyphenoxy)-N-methyl-3-phenylpropylamine, N-methyl-gamma-(2-methylphenoxy)phenylpropanolamine 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Most antidepressants elicit their therapeutic benefits through selective blockade of Na+/Cl−-coupled neurotransmitter… Expand
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Highly Cited
2002
Highly Cited
2002
Selective blockers of the norepinephrine transporter (NET) inhibit dopamine uptake in the prefrontal cortex. This suggests that… Expand
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Highly Cited
2002
Highly Cited
2002
Cocaine blocks uptake by neuronal plasma membrane transporters for dopamine, serotonin and norepinephrine, producing subjective… Expand
Highly Cited
2001
Highly Cited
2001
Parkinson's disease (PD) is characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta… Expand
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Highly Cited
1992
Highly Cited
1992
  • S. Tejani-Butt
  • The Journal of pharmacology and experimental…
  • 1992
  • Corpus ID: 7286251
The uptake sites for norepinephrine (NE) in brain have not been studied in much detail, probably due to the absence of an… Expand
Highly Cited
1989
Highly Cited
1989
Specific binding sites for [3H]cocaine were identified in caudate-putamen membranes prepared from nonhuman primate brains (Macaca… Expand
Highly Cited
1975
Highly Cited
1975
3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine (Lilly 110140) competitively inhibited the uptake of serotonin (5-HT… Expand
Highly Cited
1975
Highly Cited
1975
3-(p-Trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine (Lilly 110140), when injected into rats at i.p. doses of 1 to 10 mg/kg… Expand
Highly Cited
1974
Highly Cited
1974
Abstract Lilly 110140 is a highly selective inhibitor of serotonin uptake into synaptosomes of rat brain, unlike previous… Expand
Highly Cited
1974
Highly Cited
1974
Summary Lilly 110140 is an inhibitor of serotonin uptake by brain synaptosomes. In rats, it had no effect on brain levels of… Expand