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Fluoxetine

Known as: (+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine, Fluoxetine [Chemical/Ingredient], Fluoxetinum 
The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Understanding the physiopathology of affective disorders and their treatment relies on the availability of experimental models… Expand
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Highly Cited
2008
Highly Cited
2008
We investigated whether fluoxetine, a widely prescribed medication for treatment of depression, restores neuronal plasticity in… Expand
Highly Cited
2006
Highly Cited
2006
Chronic treatment with antidepressants increases neurogenesis in the adult hippocampus. This increase in the production of new… Expand
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Highly Cited
2003
Highly Cited
2003
Various chronic antidepressant treatments increase adult hippocampal neurogenesis, but the functional importance of this… Expand
Highly Cited
2003
Highly Cited
2003
BACKGROUND Despite the longer duration of the depressive phase in bipolar disorder and the frequent clinical use of… Expand
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Highly Cited
2003
Highly Cited
2003
Adult hippocampal neurogenesis has been demonstrated in several species and is regulated by both environmental and… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Treatment of major depression with antidepressants is generally associated with a delay in onset of clinical response… Expand
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Review
1999
Review
1999
It is now nearly 5 years since the last of the currently recognised 5-HT receptors was identified in terms of its cDNA sequence… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Depression is a major cause of morbidity and mortality in children and adolescents. To date, randomized, controlled… Expand
Highly Cited
1992
Highly Cited
1992
BACKGROUND Amitriptyline reduces the pain caused by peripheral-nerve disease, but treatment is often limited by side effects… Expand