lacosamide

Known as: N-benzyl-AcMeOPrNH2, N-benzyl-2-acetamido-3-methoxypropionamide, Erlosamide 
A functionalized amino acid compound specifically synthesized as an anticonvulsive drug to use as add-on therapy for partial-onset seizures with… (More)
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Status epilepticus is among the most common neurologic emergencies, with a mortality rate of up to 20%. The most important… (More)
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2011
2011
OBJECTIVES Treatment of established status epilepticus (SE) requires immediate intravenous anticonvulsant therapy. Currently used… (More)
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2011
2011
Lacosamide (LCM) is an antiepileptic drug (AED) that has demonstrated a good efficacy in controlling seizures as an add-on in… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE To evaluate the efficacy and safety of lacosamide (400 and 600 mg/day) as adjunctive treatment in patients with… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE To evaluate the efficacy and safety of lacosamide (200 and 400 mg/day) when added to one to three concomitant… (More)
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Highly Cited
2008
Highly Cited
2008
We hypothesized that lacosamide modulates voltage-gated sodium channels (VGSCs) at clinical concentrations (32-100 muM… (More)
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2008
2008
PURPOSE This multicenter, double-blind, double-dummy, randomized, inpatient trial evaluated the safety, tolerability, and… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE To evaluate the efficacy and safety of lacosamide when added to 1 or 2 antiepileptic drugs (AEDs) in adults with… (More)
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2007
2007
BACKGROUND Peripheral diabetic neuropathy affects between 20% and 45% of patients with diabetes. OBJECTIVE To ascertain the… (More)
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2007
2007
The etiology of osteoarthritis is multifactorial, with inflammatory, metabolic, and mechanical causes. Pain in osteoarthritis is… (More)
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