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lacosamide
Known as:
N-benzyl-AcMeOPrNH2
, N-benzyl-2-acetamido-3-methoxypropionamide
, Erlosamide
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A functionalized amino acid compound specifically synthesized as an anticonvulsive drug to use as add-on therapy for partial-onset seizures with…
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National Institutes of Health
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Related topics
Related topics
11 relations
20 ML lacosamide 10 MG/ML Injection [Vimpat]
Antiepileptic Agents
Epilepsy
Harkoseride
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Broader (2)
Acetamides
Anticonvulsants
Narrower (1)
Vimpat
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Antagonistic interaction of lacosamide with carbamazepine and valproate in the mouse tonic-clonic seizure model
Maria W. Kondrat-Wróbel
,
Katarzyna Załuska
,
+4 authors
J. Łuszczki
Health Problems of Civilization
2019
Corpus ID: 109295458
and valproate (VPA) at the fixed-ratio of 1:1:1 in the mouse tonic-clonic seizure model. Material and methods. Male albino Swiss…
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2015
2015
NEWER ANALYTICAL VALIDATION OF LACOSAMIDE IN BULK AND THEIR TABLET DOSAGE FORM BY RP-UPLC
R. Valarmathi
,
R. Senthamarai
,
S. Akilandeswari
,
S. Farisha
,
V. Revathi
2015
Corpus ID: 97816876
A new sample, precise, accurate, sensitive, less time consuming isocratic Reverse Phase Ultra Performance Liquid Chromatography…
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2014
2014
Development and Validation of Stability Indicating RP-HPLC Method for Estimation of Lacosamide in Bulk and its Pharmaceutical Formulations
S. Patil
,
A. Kadam
2014
Corpus ID: 98707857
An isocratic reverse phase High Performance liquid chromatography (RP-HPLC) method has been developed and subsequently validated…
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2014
2014
LIQUID CHROMATOGRAPHIC ASSAY OF LACOSAMIDE IN HUMAN PLASMA USING LIQUID- LIQUID EXTRACTION
M. Reddy
2014
Corpus ID: 97870138
The main objective of the study was to develop and validate a simple, rapid, selective, accurate, sensitive, robust and…
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2014
2014
NEUROPROTECTIVE EFFECT OF LACOSAMIDE AND PREGABALIN ON STRYCHNINE INDUCED SEIZURE MODELS IN RAT
M. Abraham
,
K. P. Mohamed Faisal
,
C. Biju
,
G.Babu
,
Devaki Amma Memorial
2014
Corpus ID: 74622614
Clinical and experimental data indicate that epilepsy may lead to neuronal death and lesions placed in diverse brain regions…
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2012
2012
A Stability-Indicating Liquid Chromatographic Method for the Quantification of New Anti-Epileptic Drug Lacosamide and its Intermediates
Parmar
,
Nimavat Ks
,
Vyas Kb
,
Rao Dvns
,
R. Pande
2012
Corpus ID: 97404185
A simple, selective, precise, and stability-indicating high performance liquid chromatography (HPLC) method has been established…
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2012
2012
STABILITY INDICATING HPLC METHOD FOR DETERMINATION OF LACOSAMIDE AND ITS DEGRADANTS/IMPURITIES IN BULK AND PHARMACEUTICAL FORMULATION
V. Chakravarthy
,
D. Sankar
2012
Corpus ID: 98646209
A reverse phase liquid chromatography (RP-LC) method has been developed and subsequently validated for the determination of…
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2011
2011
Development and validation of a stability-indicating RP - HPLC method for determination of lacosamide
V. Sreenivasulu
,
D. R. Rao
,
Umarov Bn
,
Samar K. Das
,
Abburi
2011
Corpus ID: 98734948
A novel stability-indicating reverse phase high pressure liquid chromatographic assay method was developed and validated for the…
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2011
2011
Development and validation of stability-indicating assay method for lacosamide by RP- HPLC
Sachin N. Shah
,
S. Vasantharaju
,
Arumugam Karthik
,
B. Muddukrishna
2011
Corpus ID: 100973261
The present study describes degradation of Lacosamide under various conditions like, oxidation, hydrolysis, and thermal stress…
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2009
2009
Synthesis of Lacosamide
Yin-Ling Ma
,
Feng Zhao
,
Kai Zhang
,
Lei-Na Liu
,
Yu-Min Du
2009
Corpus ID: 101803310
Lacosamide,an anticonvulsant was synthesized from D-serine by protection with(Boc)_2O, O-methylation with(CH_3)_-2SO_4 and…
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