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alpha-methyl-4-carboxyphenylglycine

Known as: 2-methyl-4-carboxyphenylglycine, alpha-MCPG, alpha-methyl-CPGly 
National Institutes of Health

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Related topics

5 relations

Broader (3)

BenzoatesExcitatory Amino Acid AntagonistsGlycine

Narrower (1)

LY-367385
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
In vitro models of traumatic brain injury.
In vitro models of traumatic brain injury (TBI) are helping elucidate the pathobiological mechanisms responsible for dysfunction… 
Highly Cited
2001
Highly Cited
2001
Mechanisms of adenosine 5′‐triphosphate‐induced dopamine release in the rat nucleus accumbens in vivo
The endogenous mechanisms modulating ATP‐induced dopamine release in the nucleus accumbens (NAc) were studied by microdialysis in… 
Highly Cited
2000
Highly Cited
2000
Elevation of intradendritic sodium concentration mediated by synaptic activation of metabotropic glutamate receptors in cerebellar Purkinje cells
Cerebellar Purkinje cells express both ionotropic glutamate receptors and metabotropic glutamate receptors. Brief tetanic… 
Highly Cited
1999
Highly Cited
1999
1‐Aminoindan‐1,5‐dicarboxylic acid and (S)‐(+)‐2‐(3′‐carboxybicyclo[1.1.1] pentyl)‐glycine, two mGlu1 receptor‐preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral…
Metabotropic glutamate (mGlu) receptors have been implicated in a number of physiological and pathological responses to glutamate… 
Highly Cited
1997
Highly Cited
1997
Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides
ori-beta is a well-characterized origin of bidirectional replication (OBR) located approximately 17 kb downstream of the… 
Highly Cited
1997
Highly Cited
1997
A Slow Excitatory Postsynaptic Current Mediated by G‐protein‐coupled Metabotropic Glutamate Receptors in Rat Ventral Tegmental Dopamine Neurons
Dopamine neurons in the substantia nigra and ventral tegmental area express metabotropic glutamate receptors, but activation of… 
Highly Cited
1996
Highly Cited
1996
Contrast adaptation and excitatory amino acid receptors in cat striate cortex
Abstract We have employed two paradigms to investigate the mechanisms of contrast gain control in cat striate cortex. In the… 
1995
1995
Evidence against a role for metabotropic glutamate receptors in mossy fiber LTP: the use of mutant mice and pharmacological antagonists
Highly Cited
1994
Highly Cited
1994
Activation of metabotropic glutamate receptors is necessary for long-term potentiation in the dentate gyrus and for spatial learning
Highly Cited
1993
Highly Cited
1993
(RS)-alpha-methyl-4-carboxyphenylglycine neither prevents induction of LTP nor antagonizes metabotropic glutamate receptors in CA1 hippocampal neurons.
1. The effects of the putative antagonist of metabotropic glutamate receptors (mGluR), (RS)-alpha-methyl-4-carboxyphenylglycine… 
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